SCOP 1.63: Family c.1.2.4: Tryptophan biosynthesis enzymes

Lineage for Family c.1.2.4: Tryptophan biosynthesis enzymes

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (4 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (3 proteins)

Proteins:

1. Indole-3-glycerophosphate synthase, IPGS [51385] (3 species)

   1. Species Archaeon Sulfolobus solfataricus [TaxId:2287] [51387] (6 PDB entries)

   2. Species Escherichia coli [TaxId:562] [51386] (2 PDB entries)
      merged in bifunctional enzyme with PRA isomerase

   3. Species Thermotoga maritima, TM0140 [75052] (2 PDB entries)
      TM0140

2. N-(5'phosphoribosyl)antranilate isomerase, PRAI [51382] (2 species)

   1. Species Escherichia coli [TaxId:562] [51383] (1 PDB entry)
      merged in bifunctional enzyme with IPG synthase

   2. Species Thermotoga maritima [TaxId:243274] [51384] (3 PDB entries)

3. Trp synthase alpha-subunit [51388] (2 species)

   1. Species Archaeon Pyrococcus furiosus [TaxId:2261] [51390] (1 PDB entry)

   2. Species Salmonella typhimurium [TaxId:90371] [51389] (31 PDB entries)

More info for Family c.1.2.4: Tryptophan biosynthesis enzymes

Timeline for Family c.1.2.4: Tryptophan biosynthesis enzymes:

• Family c.1.2.4: Tryptophan biosynthesis enzymes first appeared (with stable ids) in SCOP 1.55
  
• Family c.1.2.4: Tryptophan biosynthesis enzymes appears in SCOP 1.61
  
• Family c.1.2.4: Tryptophan biosynthesis enzymes appears in SCOP 1.65
  
• Family c.1.2.4: Tryptophan biosynthesis enzymes appears in the current release, SCOPe 2.08