SCOPe 2.01: Family c.1.2.3: Decarboxylase

Lineage for Family c.1.2.3: Decarboxylase

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.3: Decarboxylase [51375] (4 proteins)

Proteins:

1. 3-keto-L-gulonate 6-phosphate decarboxylase [75050] (2 species)

   1. Species Escherichia coli [TaxId:562] [75051] (14 PDB entries)
      Uniprot P39304

   2. Species Streptococcus mutans [TaxId:1309] [188972] (3 PDB entries)

2. Orotidine 5'-monophosphate decarboxylase (OMP decarboxylase) [51376] (7 species)

   1. Species Bacillus subtilis [TaxId:1423] [51377] (1 PDB entry)

   2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51380] (2 PDB entries)

   3. Species Escherichia coli [TaxId:562] [51378] (3 PDB entries)

   4. Species Methanobacterium thermoautotrophicum [TaxId:145262] [51379] (18 PDB entries)

   5. Species Plasmodium vivax [TaxId:5855] [141747] (1 PDB entry)

   6. Species Pyrococcus horikoshii [TaxId:53953] [141748] (4 PDB entries)
      Uniprot O58462 1-208

   7. Species Thermotoga maritima [TaxId:2336] [141746] (1 PDB entry)
      Uniprot Q9WYG7 1-198

3. Protozoan orotidine monophosphate decarboxylase [141749] (5 species)

   1. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141751] (1 PDB entry)
      Uniprot Q8T6J6 1-323

   2. Species Plasmodium berghei [TaxId:5821] [141752] (1 PDB entry)
      Uniprot Q4Z4C3 2-325

   3. Species Plasmodium falciparum (isolate 3D7) (Plasmodium falciparum 3D7) [TaxId:36329] [159376] (5 PDB entries)

   4. Species Plasmodium vivax [TaxId:5855] [141750] (1 PDB entry)

   5. Species Plasmodium yoelii [TaxId:5861] [141753] (1 PDB entry)
      Uniprot Q7RPE4 2-322

4. automated matches [190130] (9 species)
   not a true protein

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188935] (5 PDB entries)

   2. Species Escherichia coli [TaxId:562] [186853] (1 PDB entry)

   3. Species Geobacillus kaustophilus [TaxId:235909] [188260] (2 PDB entries)

   4. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [187245] (4 PDB entries)

   5. Species Methanobacterium thermoautotrophicum [TaxId:187420] [189749] (5 PDB entries)

   6. Species Methanothermobacter thermautotrophicus [TaxId:145262] [189782] (9 PDB entries)

   7. Species Methanothermobacter thermautotrophicus [TaxId:187420] [188934] (38 PDB entries)

   8. Species Plasmodium berghei [TaxId:5821] [187698] (1 PDB entry)

   9. Species Plasmodium falciparum [TaxId:36329] [187244] (4 PDB entries)

More info for Family c.1.2.3: Decarboxylase

Timeline for Family c.1.2.3: Decarboxylase:

• Family c.1.2.3: Decarboxylase first appeared (with stable ids) in SCOP 1.55, called Family c.1.2.3: Orotidine 5'-monophosphate decarboxylase (OMP decarboxylase)
  
• Family c.1.2.3: Decarboxylase appears in SCOP 1.75
  
• Family c.1.2.3: Decarboxylase appears in SCOPe 2.02
  
• Family c.1.2.3: Decarboxylase appears in the current release, SCOPe 2.08