SCOPe 2.01: Protein: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA

Lineage for Protein: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA

Root: SCOPe 2.01
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)
Family c.1.2.1: Histidine biosynthesis enzymes [51367] (3 proteins)
structural evidence for the gene duplication within the barrel fold
Protein Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA [51368] (2 species)

Species:

Streptomyces coelicolor [TaxId:1902] [141744] (2 PDB entries)
Uniprot P16250 2-240
1. Domain for 1vzw:
  - Domain d1vzwa1: 1vzw A:2-240 [120553]
    complexed with gol, so4
2. Domain for 2vep:
  - Domain d2vepa1: 2vep A:2-240 [153025]
    automatically matched to d1vzwa1
    complexed with so4
Thermotoga maritima [TaxId:2336] [51369] (2 PDB entries)
1. Domains for 1qo2:
  1. Domain d1qo2a_: 1qo2 A: [28533]
  2. Domain d1qo2b_: 1qo2 B: [28534]
2. Domains for 2cff:
  1. Domain d2cffa_: 2cff A: [163397]
    automated match to d1qo2a_
    complexed with mpd; mutant
  2. Domain d2cffb_: 2cff B: [163398]
    automated match to d1qo2a_
    complexed with mpd; mutant

More info for Protein Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA from c.1.2.1: Histidine biosynthesis enzymes

Timeline for Protein Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA from c.1.2.1: Histidine biosynthesis enzymes:

Protein Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA from c.1.2.1: Histidine biosynthesis enzymes first appeared (with stable ids) in SCOP 1.55
Protein Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA from c.1.2.1: Histidine biosynthesis enzymes appears in SCOP 1.75
Protein Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA from c.1.2.1: Histidine biosynthesis enzymes appears in SCOPe 2.02
Protein Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA from c.1.2.1: Histidine biosynthesis enzymes appears in the current release, SCOPe 2.08