Lineage for Family c.1.2.1: Histidine biosynthesis enzymes

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 383642Fold c.1: TIM beta/alpha-barrel [51350] (28 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 383803Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (4 families) (S)
  5. 383804Family c.1.2.1: Histidine biosynthesis enzymes [51367] (2 proteins)
    structural evidence for the gene duplication within the barrel fold

Proteins:

  1. 383805Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF [51370] (4 species)
    1. 383806Species Archaeon Pyrobaculum aerophilum [TaxId:13773] [69380] (1 PDB entry)
    2. 383809Species Baker's yeast (Saccharomyces cerevisiae), His7 [TaxId:4932] [69379] (4 PDB entries)
    3. 383818Species Thermotoga maritima [TaxId:243274] [51371] (3 PDB entries)
    4. 383824Species Thermus thermophilus [TaxId:274] [82237] (1 PDB entry)
  2. 383826Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA [51368] (1 species)

More info for Family c.1.2.1: Histidine biosynthesis enzymes

Timeline for Family c.1.2.1: Histidine biosynthesis enzymes: