Lineage for Family b.85.4.1: dUTPase-like

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2406647Fold b.85: beta-clip [51268] (7 superfamilies)
    double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll
  4. 2406808Superfamily b.85.4: dUTPase-like [51283] (2 families) (S)
    forms tight trimer through an additional beta-sheet in each subunit
    subunit beta-sheets are orthogonally packed around the three-fold axis
  5. 2406809Family b.85.4.1: dUTPase-like [51284] (5 protein domains)

Protein Domains:

  1. 2406810Bifunctional dCTP deaminase/dUTPase [89425] (1 species)
    elaborated fold with additional structures
  2. 2406822Deoxycytidine triphosphate deaminase (dCTP deaminase) [117335] (2 species)
    1. 2406823Species Escherichia coli [TaxId:562] [117336] (6 PDB entries)
      Uniprot P28248
    2. 2406858Species Mycobacterium tuberculosis [TaxId:83332] [188349] (3 PDB entries)
  3. 2406879Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) [51285] (7 species)
    1. 2406880Species Equine infectious anemia virus [TaxId:11665] [51288] (2 PDB entries)
    2. 2406883Species Escherichia coli [TaxId:562] [51286] (10 PDB entries)
      Uniprot P06968
    3. 2406894Species Feline immunodeficiency virus [TaxId:11673] [51287] (8 PDB entries)
    4. 2406913Species Human (Homo sapiens) [TaxId:9606] [102010] (2 PDB entries)
    5. 2406920Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141654] (1 PDB entry)
      Uniprot Q8II92 1-159
    6. 2406922Species Mycobacterium tuberculosis, rv2697c [TaxId:1773] [82213] (8 PDB entries)
    7. 2406941Species Vaccinia virus [TaxId:10245] [187961] (5 PDB entries)
  4. 2406957Monomeric viral dUTPase [141655] (1 species)
    related to the trimeric dUTPase domain by domain duplication, fusion and partial deletion; retains only one of the three ancestral active sites
  5. 2406963automated matches [190798] (8 species)
    not a true protein
    1. 2406964Species Burkholderia thailandensis [TaxId:271848] [235375] (1 PDB entry)
    2. 2406966Species Chlorella variabilis [TaxId:554065] [195003] (1 PDB entry)
    3. 2406968Species Coxiella burnetii [TaxId:777] [196147] (1 PDB entry)
    4. 2406970Species Human herpesvirus 4 [TaxId:10377] [231386] (4 PDB entries)
    5. 2406979Species Methanocaldococcus jannaschii [TaxId:2190] [226814] (2 PDB entries)
    6. 2406982Species Mycobacterium abscessus [TaxId:561007] [226542] (1 PDB entry)
    7. 2406984Species Mycobacterium tuberculosis [TaxId:1773] [189128] (6 PDB entries)
    8. 2406991Species Plasmodium falciparum [TaxId:36329] [188061] (4 PDB entries)

More info for Family b.85.4.1: dUTPase-like

Timeline for Family b.85.4.1: dUTPase-like: