SCOP 1.73: Protein: Isopenicillin N synthase

Lineage for Protein: Isopenicillin N synthase

Root: SCOP 1.73
Class b: All beta proteins [48724] (165 folds)

Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
one turn of helix is made by two pairs of antiparallel strands linked with short turns
has appearance of a sandwich of distinct architecture and jelly-roll topology

Superfamily b.82.2: Clavaminate synthase-like [51197] (12 families)
Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
Family b.82.2.1: Penicillin synthase-like [51198] (4 proteins)
common fold is rather distorted
Protein Isopenicillin N synthase [51199] (1 species)

Species:

Emericella nidulans [TaxId:162425] [51200] (25 PDB entries)
1. Domain for 1bk0:
  - Domain d1bk0a_: 1bk0 A: [28118]
    complexed with acv, fe, so4
2. Domain for 1blz:
  - Domain d1blza_: 1blz A: [28120]
    complexed with acv, fe, no
3. Domain for 1hb1:
  - Domain d1hb1a_: 1hb1 A: [65748]
    complexed with fe2, ocv, so4
4. Domain for 1hb2:
  - Domain d1hb2a_: 1hb2 A: [65749]
    complexed with fe2, scv, so4
5. Domain for 1hb3:
  - Domain d1hb3a_: 1hb3 A: [65750]
    complexed with fe2, scv, so4
6. Domain for 1hb4:
  - Domain d1hb4a_: 1hb4 A: [65751]
    complexed with fe2, scv, so4
7. Domains for 1ips:
  1. Domain d1ipsa_: 1ips A: [28122]
  2. Domain d1ipsb_: 1ips B: [28123]
    complexed with mn
8. Domain for 1obn:
  - Domain d1obna_: 1obn A: [92763]
    complexed with asv, fe2, nmo, so4
9. Domain for 1oc1:
  - Domain d1oc1a_: 1oc1 A: [92764]
    complexed with asv, fe2, so4
10. Domain for 1odm:
  - Domain d1odma_: 1odm A: [86875]
    complexed with asv, fe2, so4
11. Domain for 1odn:
  - Domain d1odna_: 1odn A: [86876]
    complexed with apv, fe2, so4
12. Domain for 1qiq:
  - Domain d1qiqa_: 1qiq A: [28121]
    complexed with acc, fe, so4
13. Domain for 1qje:
  - Domain d1qjea_: 1qje A: [28117]
    Ip1 - Fe complex
    complexed with acv, fe2, ip1, so4
14. Domain for 1qjf:
  - Domain d1qjfa_: 1qjf A: [28119]
    monocyclic sulfoxide - Fe complex
    complexed with acs, fe2, so4
15. Domain for 1uzw:
  - Domain d1uzwa_: 1uzw A: [108183]
    complexed with cdh, fe2, so4
16. Domain for 1w03:
  - Domain d1w03a1: 1w03 A:3-331 [120556]
    automatically matched to d1bk0__
    complexed with fe2, hcg, so4
17. Domain for 1w04:
  - Domain d1w04a1: 1w04 A:3-331 [120557]
    automatically matched to d1bk0__
    complexed with fe2, hcg, no, so4
18. Domain for 1w05:
  - Domain d1w05a1: 1w05 A:3-331 [120558]
    automatically matched to d1bk0__
    complexed with fe2, so4, w05
19. Domain for 1w06:
  - Domain d1w06a1: 1w06 A:3-331 [120559]
    automatically matched to d1bk0__
    complexed with fe2, no, so4, w05
20. Domain for 1w3v:
  - Domain d1w3va1: 1w3v A:3-331 [120624]
    automatically matched to d1bk0__
    complexed with fe2, mdz
21. Domain for 1w3x:
  - Domain d1w3xa1: 1w3x A:3-331 [120625]
    automatically matched to d1bk0__
    complexed with fe2, w2x
22. Domain for 2bjs:
  - Domain d2bjsa1: 2bjs A:3-322 [128632]
    automatically matched to d1bk0__
    complexed with acv, fe, mee, so4; mutant
23. Domain for 2bu9:
  - Domain d2bu9a1: 2bu9 A:3-331 [129169]
    automatically matched to d1bk0__
    complexed with fe, hfv, so4
24. Domain for 2ivi:
  - Domain d2ivib1: 2ivi B:3-331 [137723]
    automatically matched to d1bk0__
    complexed with acw, fe2, so4
25. Domain for 2ivj:
  - Domain d2ivja1: 2ivj A:3-331 [137724]
    automatically matched to d1bk0__
    complexed with bcv, fe2, so4

More info for Protein Isopenicillin N synthase from b.82.2.1: Penicillin synthase-like

Timeline for Protein Isopenicillin N synthase from b.82.2.1: Penicillin synthase-like:

Protein Isopenicillin N synthase from b.82.2.1: Penicillin synthase-like first appeared (with stable ids) in SCOP 1.55, called Protein Isopenicillin N synthase from b.82.2.1: Penicillin syntase
Protein Isopenicillin N synthase from b.82.2.1: Penicillin synthase-like appears in SCOP 1.71
Protein Isopenicillin N synthase from b.82.2.1: Penicillin synthase-like appears in SCOP 1.75
Protein Isopenicillin N synthase from b.82.2.1: Penicillin synthase-like appears in the current release, SCOPe 2.08