SCOP 1.75: Family b.82.1.1: dTDP-sugar isomerase

Lineage for Family b.82.1.1: dTDP-sugar isomerase

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
   one turn of helix is made by two pairs of antiparallel strands linked with short turns
   has appearance of a sandwich of distinct architecture and jelly-roll topology

4. Superfamily b.82.1: RmlC-like cupins [51182] (24 families)

5. Family b.82.1.1: dTDP-sugar isomerase [51183] (4 proteins)

Proteins:

1. dTDP-4-dehydrorhamnose 3,5-epimerase RmlC [51184] (6 species)
   synonym: dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase

   1. Species Archaeon Methanobacterium thermoautotrophicum [TaxId:145262] [51186] (2 PDB entries)

   2. Species Archaeon Sulfolobus tokodaii [TaxId:111955] [141586] (1 PDB entry)
      Uniprot Q96Z62 1-176

   3. Species Mycobacterium tuberculosis [TaxId:1773] [101971] (3 PDB entries)

   4. Species Pseudomonas aeruginosa [TaxId:287] [101972] (3 PDB entries)

   5. Species Salmonella typhimurium [TaxId:90371] [51185] (2 PDB entries)

   6. Species Streptococcus suis [TaxId:1307] [89402] (4 PDB entries)

2. dTDP-4-keto-6-deoxy-glucose-5-epimerase EvaD [101973] (1 species)

   • Species Amycolatopsis orientalis [TaxId:31958] [101974] (2 PDB entries)
     Uniprot O52806

3. dTDP-6-deoxy-3,4-keto-hexulose isomerase FdtA [159287] (1 species)

   • Species Aneurinibacillus thermoaerophilus [TaxId:143495] [159288] (4 PDB entries)
     Uniprot Q6T1W8 1-136! Uniprot Q6T1W8 2-136

4. Novobiocin biosynthesis protein NovW [141587] (1 species)

   • Species Streptomyces caeruleus [TaxId:195949] [141588] (1 PDB entry)
     Uniprot Q9L9E5 1-190

More info for Family b.82.1.1: dTDP-sugar isomerase

Timeline for Family b.82.1.1: dTDP-sugar isomerase:

• Family b.82.1.1: dTDP-sugar isomerase first appeared (with stable ids) in SCOP 1.55, called Family b.82.1.1: dTDP-4-dehydrorhamnose 3,5-epimerase RmlC
  
• Family b.82.1.1: dTDP-sugar isomerase appears in SCOP 1.73
  
• Family b.82.1.1: dTDP-sugar isomerase appears in SCOPe 2.01
  
• Family b.82.1.1: dTDP-sugar isomerase appears in the current release, SCOPe 2.08