SCOPe 2.08: Family b.68.1.1: Sialidases (neuraminidases)

Lineage for Family b.68.1.1: Sialidases (neuraminidases)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
   consists of six 4-stranded beta-sheet motifs; meander

4. Superfamily b.68.1: Sialidases [50939] (3 families)

5. Family b.68.1.1: Sialidases (neuraminidases) [50940] (10 proteins)

Proteins:

1. Hemagglutinin-neuraminidase glycoprotein [101891] (1 species)

   • Species Human parainfluenza virus type 3 [TaxId:11216] [101892] (5 PDB entries)

2. Influenza neuraminidase [50943] (9 species)

   1. Species Influenza a virus (a/anhui/1-balf_rg44/2013(h7n9)) [TaxId:1481987] [395332] (1 PDB entry)

   2. Species Influenza A virus (a/chicken/nanchang/7-010/2000(h3n6)) [TaxId:215864] [311106] (2 PDB entries)

   3. Species Influenza a virus (a/environment/shanghai/s1439/2013(h7n9)) [TaxId:1347105] [377786] (3 PDB entries)

   4. Species Influenza A virus (a/mallard/alb/196/1996(h10n7)) [TaxId:352589] [311107] (2 PDB entries)

   5. Species Influenza A virus (a/northern pintail/washington/40964/2014(h5n2)) [TaxId:1589662] [346256] (1 PDB entry)

   6. Species Influenza a virus (strain a/duck/england/1/1956 h11n6) [TaxId:383550] [356823] (3 PDB entries)

   7. Species Influenza a virus (strain a/japan/305/1957 h2n2) [TaxId:387161] [419771] (1 PDB entry)

   8. Species Influenza A virus, different strains [TaxId:11320] [50944] (89 PDB entries)
      Uniprot P03472 84-470

   9. Species Influenza B virus [TaxId:11520] [50945] (20 PDB entries)

3. Leech intramolecular trans-sialidase, C-terminal domain [50948] (1 species)
   contains incomplete beta-barrel subdomain inserted in the second blade

   • Species North american leech (Macrobdella decora) [TaxId:6405] [50949] (5 PDB entries)

4. Micromonospora sialidase, N-terminal domain [50946] (1 species)

   • Species Micromonospora viridifaciens [TaxId:1881] [50947] (6 PDB entries)
     Uniprot Q02834 47-647

5. Paramyxovirus hemagglutinin-neuraminidase head domain [63823] (1 species)

   • Species Newcastle disease virus [TaxId:11176] [63824] (5 PDB entries)

6. Salmonella sialidase [50941] (1 species)

   • Species Salmonella typhimurium, strain lt2 [TaxId:90371] [50942] (5 PDB entries)

7. Sialidase 2 (Neu2) [117274] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [117275] (14 PDB entries)
     Uniprot Q9Y3R4

8. Trypanosoma sialidase [82164] (2 species)

   1. Species Trypanosoma cruzi [TaxId:5693] [89371] (13 PDB entries)
      Uniprot Q26966

   2. Species Trypanosoma rangeli [TaxId:5698] [82165] (7 PDB entries)
      Uniprot O44049 20-653

9. Vibrio cholerae sialidase [50950] (2 species)
   contains 2 additional domains of ConA-like fold

   1. Species Vibrio cholerae [TaxId:243277] [342048] (2 PDB entries)

   2. Species Vibrio cholerae [TaxId:666] [50951] (3 PDB entries)
      Uniprot P37060

10. automated matches [193245] (21 species)
    not a true protein

    1. Species Avian avulavirus 1 [TaxId:11176] [403011] (1 PDB entry)

    2. Species Human (Homo sapiens) [TaxId:9606] [228885] (2 PDB entries)

    3. Species Human parainfluenza 3 virus [TaxId:11217] [228816] (2 PDB entries)

    4. Species Human parainfluenza virus 3 [TaxId:11216] [270133] (5 PDB entries)

    5. Species Human respirovirus 3 [TaxId:11216] [353948] (1 PDB entry)

    6. Species Influenza A virus (a/chicken/sichuan/ncjpl1/2014(h5n6)) [TaxId:1529593] [315491] (1 PDB entry)

    7. Species Influenza a virus (a/hunan/02650/2016(h7n9) [TaxId:1332244] [377789] (1 PDB entry)

    8. Species Influenza a virus (a/minnesota/11/2010(h3n2)) [TaxId:1507381] [370710] (1 PDB entry)

    9. Species Influenza a virus (a/shanghai/02/2013(h7n9)) [TaxId:1332244] [377802] (2 PDB entries)

    10. Species Influenza A virus [TaxId:119210] [193455] (7 PDB entries)

    11. Species Influenza A virus [TaxId:382827] [193246] (9 PDB entries)

    12. Species Influenza A virus, different strains [TaxId:11320] [255029] (1 PDB entry)

    13. Species Influenza B virus (b/brisbane/60/2008) [TaxId:604436] [256640] (3 PDB entries)

    14. Species Influenza B virus [TaxId:11520] [256642] (3 PDB entries)

    15. Species Micromonospora viridifaciens [TaxId:1881] [254941] (4 PDB entries)

    16. Species Mumps rubulavirus [TaxId:1979165] [369137] (2 PDB entries)

    17. Species Mumps virus [TaxId:11161] [323195] (2 PDB entries)

    18. Species Simian virus 5 [TaxId:11207] [346257] (6 PDB entries)

    19. Species Trypanosoma cruzi [TaxId:5693] [226151] (1 PDB entry)

    20. Species Trypanosoma rangeli [TaxId:5698] [255026] (3 PDB entries)

    21. Species Unidentified influenza virus [TaxId:11309] [364248] (1 PDB entry)

More info for Family b.68.1.1: Sialidases (neuraminidases)

Timeline for Family b.68.1.1: Sialidases (neuraminidases):

• Family b.68.1.1: Sialidases (neuraminidases) first appeared (with stable ids) in SCOP 1.55
  
• Family b.68.1.1: Sialidases (neuraminidases) appears in SCOPe 2.07