SCOPe 2.01: Superfamily b.68.1: Sialidases

Lineage for Superfamily b.68.1: Sialidases

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
   consists of six 4-stranded beta-sheet motifs; meander

4. Superfamily b.68.1: Sialidases [50939] (3 families)

Families:

1. b.68.1.1: Sialidases (neuraminidases) [50940] (10 proteins)

2. b.68.1.2: Endo-alpha-sialidase [117276] (1 protein)
   possibly related by the other family by circular permutation; includes extra N-terminal domain [dN: alpha/beta ] and insert domain [dI: beta-barrel, similar to the Reductase/isomerase/elongation factor common domain (50412)]

3. b.68.1.0: automated matches [191452] (1 protein)
   not a true family

More info for Superfamily b.68.1: Sialidases

Timeline for Superfamily b.68.1: Sialidases:

• Superfamily b.68.1: Sialidases first appeared (with stable ids) in SCOP 1.55, called Superfamily b.68.1: Sialidases (neuraminidases)
  
• Superfamily b.68.1: Sialidases appears in SCOP 1.75
  
• Superfamily b.68.1: Sialidases appears in SCOPe 2.02
  
• Superfamily b.68.1: Sialidases appears in the current release, SCOPe 2.08