Lineage for Protein: Cyclophilin (eukaryotic)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 806745Fold b.62: Cyclophilin-like [50890] (1 superfamily)
    barrel, closed; n=8, S=10; complex topology
  4. 806746Superfamily b.62.1: Cyclophilin-like [50891] (4 families) (S)
  5. 806747Family b.62.1.1: Cyclophilin (peptidylprolyl isomerase) [50892] (12 proteins)
  6. 806748Protein Cyclophilin (eukaryotic) [50893] (13 species)

Species:

  1. 806749Aspergillus fumigatus [TaxId:5085] [141499] (1 PDB entry)
    Uniprot Q9Y7F6 8-178
  2. 806752Baker's yeast (Saccharomyces cerevisiae), variant A [TaxId:4932] [101878] (2 PDB entries)
    1. Domains for 1ist:
      1. 806754Domain d1ista_: 1ist A: [90692]
      2. 806755Domain d1istb_: 1ist B: [90693]
    2. Domain for 1vdn:
  3. 806756Caenorhabditis elegans, isoform 3 [TaxId:6239] [50899] (5 PDB entries)
    1. Domain for 1dyw:
    2. Domain for 1e3b:
    3. Domain for 1e8k:
    4. Domain for 2igv:
    5. Domain for 2igw:
  4. 806762Caenorhabditis elegans, isoform 5 [TaxId:6239] [82161] (1 PDB entry)
  5. 806764Human (Homo sapiens), U4/U6 snRNP-specific cyclophilin snucyp-20 [TaxId:9606] [50896] (2 PDB entries)
    1. Domain for 1mzw:
      • 806766Domain d1mzwa_: 1mzw A: [91503]
        complexed with a 30-residue peptide from U4/U6 snRNP 60kda protein, chain B
    2. Domain for 1qoi:
  6. 806767Human (Homo sapiens), variant A [TaxId:9606] [50894] (48 PDB entries)
    Uniprot P05092
    1. Domains for 1ak4:
      1. 806845Domain d1ak4a_: 1ak4 A: [27472]
        Other proteins in same PDB: d1ak4c_, d1ak4d_
      2. 806846Domain d1ak4b_: 1ak4 B: [27473]
        Other proteins in same PDB: d1ak4c_, d1ak4d_
        mutant
    2. Domain for 1awq:
    3. Domains for 1awr:
      1. 806839Domain d1awra_: 1awr A: [27464]
      2. 806840Domain d1awrb_: 1awr B: [27465]
      3. 806841Domain d1awrc_: 1awr C: [27466]
      4. 806842Domain d1awrd_: 1awr D: [27467]
      5. 806843Domain d1awre_: 1awr E: [27468]
      6. 806844Domain d1awrf_: 1awr F: [27469]
    4. Domain for 1aws:
    5. Domains for 1awt:
      1. 806858Domain d1awta_: 1awt A: [27481]
      2. 806859Domain d1awtb_: 1awt B: [27482]
      3. 806860Domain d1awtc_: 1awt C: [27483]
      4. 806861Domain d1awtd_: 1awt D: [27484]
      5. 806862Domain d1awte_: 1awt E: [27485]
      6. 806863Domain d1awtf_: 1awt F: [27486]
        mutant
    6. Domain for 1awu:
    7. Domains for 1awv:
      1. 806851Domain d1awva_: 1awv A: [27475]
      2. 806852Domain d1awvb_: 1awv B: [27476]
      3. 806853Domain d1awvc_: 1awv C: [27477]
      4. 806854Domain d1awvd_: 1awv D: [27478]
      5. 806855Domain d1awve_: 1awv E: [27479]
      6. 806856Domain d1awvf_: 1awv F: [27480]
    8. Domain for 1bck:
    9. Domain for 1cwa:
    10. Domain for 1cwb:
    11. Domain for 1cwc:
    12. Domain for 1cwf:
    13. Domain for 1cwh:
    14. Domain for 1cwi:
    15. Domain for 1cwj:
    16. Domain for 1cwk:
    17. Domain for 1cwl:
    18. Domain for 1cwm:
    19. Domain for 1cwo:
    20. Domain for 1fgl:
    21. Domains for 1m63:
      1. 806849Domain d1m63c_: 1m63 C: [78679]
        Other proteins in same PDB: d1m63a_, d1m63b_, d1m63e_, d1m63f_
        complexed with calcineurin and cyclosporin (chain D and H)
      2. 806850Domain d1m63g_: 1m63 G: [78682]
        Other proteins in same PDB: d1m63a_, d1m63b_, d1m63e_, d1m63f_
        complexed with calcineurin and cyclosporin (chain D and H)
        complexed with aba, bmt, ca, dal, fe, mle, mva, sar, zn
    22. Domains for 1m9c:
      1. 806829Domain d1m9ca_: 1m9c A: [84886]
        Other proteins in same PDB: d1m9cc_, d1m9cd_
      2. 806830Domain d1m9cb_: 1m9c B: [84887]
        Other proteins in same PDB: d1m9cc_, d1m9cd_
    23. Domains for 1m9d:
      1. 806795Domain d1m9da_: 1m9d A: [84890]
        Other proteins in same PDB: d1m9dc_, d1m9dd_
      2. 806796Domain d1m9db_: 1m9d B: [84891]
        Other proteins in same PDB: d1m9dc_, d1m9dd_
        mutant
    24. Domains for 1m9e:
      1. 806787Domain d1m9ea_: 1m9e A: [84894]
        Other proteins in same PDB: d1m9ec_, d1m9ed_
      2. 806788Domain d1m9eb_: 1m9e B: [84895]
        Other proteins in same PDB: d1m9ec_, d1m9ed_
        mutant
    25. Domains for 1m9f:
      1. 806776Domain d1m9fa_: 1m9f A: [84898]
        Other proteins in same PDB: d1m9fc_, d1m9fd_
      2. 806777Domain d1m9fb_: 1m9f B: [84899]
        Other proteins in same PDB: d1m9fc_, d1m9fd_
        mutant
    26. Domains for 1m9x:
      1. 806778Domain d1m9xa_: 1m9x A: [84905]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      2. 806779Domain d1m9xb_: 1m9x B: [84906]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      3. 806780Domain d1m9xe_: 1m9x E: [84909]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      4. 806781Domain d1m9xf_: 1m9x F: [84910]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
        mutant
    27. Domains for 1m9y:
      1. 806797Domain d1m9ya_: 1m9y A: [84913]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      2. 806798Domain d1m9yb_: 1m9y B: [84914]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      3. 806799Domain d1m9ye_: 1m9y E: [84917]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      4. 806800Domain d1m9yf_: 1m9y F: [84918]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
        mutant
    28. Domain for 1mf8:
    29. Domain for 1mik:
    30. Domains for 1nmk:
      1. 806791Domain d1nmka_: 1nmk A: [85875]
      2. 806792Domain d1nmkb_: 1nmk B: [85876]
        complexed with sfm
    31. Domain for 1oca:
    32. Domains for 1rmh:
      1. 806837Domain d1rmha_: 1rmh A: [27470]
      2. 806838Domain d1rmhb_: 1rmh B: [27471]
        complexed with nit, sin
    33. Domain for 1vbs:
    34. Domains for 1vbt:
      1. 806835Domain d1vbta_: 1vbt A: [27462]
      2. 806836Domain d1vbtb_: 1vbt B: [27463]
        complexed with alt, nit
    35. Domain for 1w8l:
    36. Domain for 1w8m:
    37. Domain for 1w8v:
    38. Domains for 1ynd:
      1. 806769Domain d1ynda1: 1ynd A:2-165 [123721]
        automatically matched to d1ak4a_
        complexed with sfa
      2. 806770Domain d1yndb1: 1ynd B:2-165 [123722]
        automatically matched to d1ak4a_
        complexed with sfa
    39. Domains for 1zkf:
      1. 806833Domain d1zkfa1: 1zkf A:2-165 [125192]
        automatically matched to d1ak4a_
        complexed with nit, sin
      2. 806834Domain d1zkfb1: 1zkf B:2-165 [125193]
        automatically matched to d1ak4a_
        complexed with nit, sin
    40. Domain for 2alf:
    41. Domain for 2cpl:
    42. Domain for 2cyh:
    43. Domains for 2rma:
      1. 806804Domain d2rmaa_: 2rma A: [27435]
      2. 806805Domain d2rmac_: 2rma C: [27436]
      3. 806806Domain d2rmae_: 2rma E: [27437]
      4. 806807Domain d2rmag_: 2rma G: [27438]
      5. 806808Domain d2rmai_: 2rma I: [27439]
      6. 806809Domain d2rmak_: 2rma K: [27440]
      7. 806810Domain d2rmam_: 2rma M: [27441]
      8. 806811Domain d2rmao_: 2rma O: [27442]
      9. 806812Domain d2rmaq_: 2rma Q: [27443]
      10. 806813Domain d2rmas_: 2rma S: [27444]
        complexed with aba
    44. Domains for 2rmb:
      1. 806815Domain d2rmba_: 2rmb A: [27446]
      2. 806816Domain d2rmbc_: 2rmb C: [27447]
      3. 806817Domain d2rmbe_: 2rmb E: [27448]
      4. 806818Domain d2rmbg_: 2rmb G: [27449]
      5. 806819Domain d2rmbi_: 2rmb I: [27450]
      6. 806820Domain d2rmbk_: 2rmb K: [27451]
      7. 806821Domain d2rmbm_: 2rmb M: [27452]
      8. 806822Domain d2rmbo_: 2rmb O: [27453]
      9. 806823Domain d2rmbq_: 2rmb Q: [27454]
      10. 806824Domain d2rmbs_: 2rmb S: [27455]
        complexed with aba, dmt
    45. Domain for 3cyh:
    46. Domain for 3cys:
    47. Domain for 4cyh:
    48. Domain for 5cyh:
  7. 806866Human (Homo sapiens), variant B [TaxId:9606] [50895] (1 PDB entry)
  8. 806868Human (Homo sapiens), variant C [TaxId:9606] [141498] (1 PDB entry)
    Uniprot P45877 32-212
  9. 806875Mouse (Mus musculus), variant C [TaxId:10090] [50897] (1 PDB entry)
  10. 806880Nematode (Brugia malayi) [TaxId:6279] [50898] (3 PDB entries)
    1. Domain for 1a33:
    2. Domain for 1a58:
    3. Domains for 1c5f:
      1. 806883Domain d1c5fa_: 1c5f A: [27497]
      2. 806884Domain d1c5fc_: 1c5f C: [27498]
      3. 806885Domain d1c5fe_: 1c5f E: [27499]
      4. 806886Domain d1c5fg_: 1c5f G: [27500]
      5. 806887Domain d1c5fi_: 1c5f I: [27501]
      6. 806888Domain d1c5fk_: 1c5f K: [27502]
      7. 806889Domain d1c5fm_: 1c5f M: [27503]
      8. 806890Domain d1c5fo_: 1c5f O: [27504]
  11. 806891Plasmodium falciparum [TaxId:5833] [50900] (2 PDB entries)
    1. Domain for 1qng:
    2. Domains for 1qnh:
      1. 806893Domain d1qnha_: 1qnh A: [27508]
      2. 806894Domain d1qnhb_: 1qnh B: [27509]
        complexed with aba; mutant
  12. 806895Plasmodium yoelii [TaxId:5861] [141500] (1 PDB entry)
    Uniprot Q7RSH5 25-210
  13. 806897Trypanosoma cruzi [TaxId:5693] [117269] (2 PDB entries)
    Uniprot Q4DPB9 30-194
    1. Domains for 1xo7:
      1. 806898Domain d1xo7a_: 1xo7 A: [115694]
        Structural genomics target
      2. 806899Domain d1xo7b_: 1xo7 B: [115695]
        Structural genomics target
      3. 806900Domain d1xo7c_: 1xo7 C: [115696]
        Structural genomics target
      4. 806901Domain d1xo7d_: 1xo7 D: [115697]
        Structural genomics target
    2. Domains for 1xq7:
      1. 806902Domain d1xq7a_: 1xq7 A: [115831]
        Structural genomics target
      2. 806903Domain d1xq7b_: 1xq7 B: [115832]
        Structural genomics target
      3. 806904Domain d1xq7c_: 1xq7 C: [115833]
        Structural genomics target
        complexed with aba

More info for Protein Cyclophilin (eukaryotic) from b.62.1.1: Cyclophilin (peptidylprolyl isomerase)

Timeline for Protein Cyclophilin (eukaryotic) from b.62.1.1: Cyclophilin (peptidylprolyl isomerase):