Lineage for Protein: Cyclophilin (eukaryotic)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 565060Fold b.62: Cyclophilin-like [50890] (1 superfamily)
    barrel, closed; n=8, S=10; complex topology
  4. 565061Superfamily b.62.1: Cyclophilin-like [50891] (2 families) (S)
  5. 565062Family b.62.1.1: Cyclophilin (peptidylprolyl isomerase) [50892] (3 proteins)
  6. 565063Protein Cyclophilin (eukaryotic) [50893] (10 species)

Species:

  1. 565064Baker's yeast (Saccharomyces cerevisiae), variant A [TaxId:4932] [101878] (1 PDB entry)
  2. 565067Caenorhabditis elegans, isoform 3 [TaxId:6239] [50899] (3 PDB entries)
    1. Domain for 1dyw:
    2. Domain for 1e3b:
    3. Domain for 1e8k:
  3. 565071Caenorhabditis elegans, isoform 5 [TaxId:6239] [82161] (1 PDB entry)
  4. 565073Human (Homo sapiens), U4/U6 snRNP-specific cyclophilin snucyp-20 [TaxId:9606] [50896] (2 PDB entries)
    1. Domain for 1mzw:
      • 565075Domain d1mzwa_: 1mzw A: [91503]
        complexed with a 30-residue peptide from U4/U6 snRNP 60kda protein, chain B
    2. Domain for 1qoi:
  5. 565076Human (Homo sapiens), variant A [TaxId:9606] [50894] (45 PDB entries)
    1. Domains for 1ak4:
      1. 565150Domain d1ak4a_: 1ak4 A: [27472]
        Other proteins in same PDB: d1ak4c_, d1ak4d_
      2. 565151Domain d1ak4b_: 1ak4 B: [27473]
        Other proteins in same PDB: d1ak4c_, d1ak4d_
        mutant
    2. Domain for 1awq:
    3. Domains for 1awr:
      1. 565140Domain d1awra_: 1awr A: [27464]
      2. 565141Domain d1awrb_: 1awr B: [27465]
      3. 565142Domain d1awrc_: 1awr C: [27466]
      4. 565143Domain d1awrd_: 1awr D: [27467]
      5. 565144Domain d1awre_: 1awr E: [27468]
      6. 565145Domain d1awrf_: 1awr F: [27469]
    4. Domain for 1aws:
    5. Domains for 1awt:
      1. 565162Domain d1awta_: 1awt A: [27481]
      2. 565163Domain d1awtb_: 1awt B: [27482]
      3. 565164Domain d1awtc_: 1awt C: [27483]
      4. 565165Domain d1awtd_: 1awt D: [27484]
      5. 565166Domain d1awte_: 1awt E: [27485]
      6. 565167Domain d1awtf_: 1awt F: [27486]
        mutant
    6. Domain for 1awu:
    7. Domains for 1awv:
      1. 565156Domain d1awva_: 1awv A: [27475]
      2. 565157Domain d1awvb_: 1awv B: [27476]
      3. 565158Domain d1awvc_: 1awv C: [27477]
      4. 565159Domain d1awvd_: 1awv D: [27478]
      5. 565160Domain d1awve_: 1awv E: [27479]
      6. 565161Domain d1awvf_: 1awv F: [27480]
    8. Domain for 1bck:
    9. Domain for 1cwa:
    10. Domain for 1cwb:
    11. Domain for 1cwc:
    12. Domain for 1cwf:
    13. Domain for 1cwh:
    14. Domain for 1cwi:
    15. Domain for 1cwj:
    16. Domain for 1cwk:
    17. Domain for 1cwl:
    18. Domain for 1cwm:
    19. Domain for 1cwo:
    20. Domain for 1fgl:
    21. Domains for 1m63:
      1. 565153Domain d1m63c_: 1m63 C: [78679]
        Other proteins in same PDB: d1m63a_, d1m63b_, d1m63e_, d1m63f_
      2. 565154Domain d1m63g_: 1m63 G: [78682]
        Other proteins in same PDB: d1m63a_, d1m63b_, d1m63e_, d1m63f_
        complexed with calcineurin and cyclosporin (chain D and H)
        complexed with aba, bmt, ca, dal, fe, mle, mva, sar, zn
    22. Domains for 1m9c:
      1. 565132Domain d1m9ca_: 1m9c A: [84886]
        Other proteins in same PDB: d1m9cc_, d1m9cd_
      2. 565133Domain d1m9cb_: 1m9c B: [84887]
        Other proteins in same PDB: d1m9cc_, d1m9cd_
    23. Domains for 1m9d:
      1. 565098Domain d1m9da_: 1m9d A: [84890]
        Other proteins in same PDB: d1m9dc_, d1m9dd_
      2. 565099Domain d1m9db_: 1m9d B: [84891]
        Other proteins in same PDB: d1m9dc_, d1m9dd_
        mutant
    24. Domains for 1m9e:
      1. 565089Domain d1m9ea_: 1m9e A: [84894]
        Other proteins in same PDB: d1m9ec_, d1m9ed_
      2. 565090Domain d1m9eb_: 1m9e B: [84895]
        Other proteins in same PDB: d1m9ec_, d1m9ed_
        mutant
    25. Domains for 1m9f:
      1. 565081Domain d1m9fa_: 1m9f A: [84898]
        Other proteins in same PDB: d1m9fc_, d1m9fd_
      2. 565082Domain d1m9fb_: 1m9f B: [84899]
        Other proteins in same PDB: d1m9fc_, d1m9fd_
        mutant
    26. Domains for 1m9x:
      1. 565083Domain d1m9xa_: 1m9x A: [84905]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      2. 565084Domain d1m9xb_: 1m9x B: [84906]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      3. 565085Domain d1m9xe_: 1m9x E: [84909]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      4. 565086Domain d1m9xf_: 1m9x F: [84910]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
        mutant
    27. Domains for 1m9y:
      1. 565100Domain d1m9ya_: 1m9y A: [84913]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      2. 565101Domain d1m9yb_: 1m9y B: [84914]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      3. 565102Domain d1m9ye_: 1m9y E: [84917]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      4. 565103Domain d1m9yf_: 1m9y F: [84918]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
        mutant
    28. Domain for 1mf8:
    29. Domain for 1mik:
    30. Domains for 1nmk:
      1. 565108Domain d1nmka_: 1nmk A: [85875]
      2. 565109Domain d1nmkb_: 1nmk B: [85876]
        complexed with sfm
    31. Domain for 1oca:
    32. Domains for 1rmh:
      1. 565148Domain d1rmha_: 1rmh A: [27470]
      2. 565149Domain d1rmhb_: 1rmh B: [27471]
        complexed with nit, sin
    33. Domain for 1vbs:
    34. Domains for 1vbt:
      1. 565146Domain d1vbta_: 1vbt A: [27462]
      2. 565147Domain d1vbtb_: 1vbt B: [27463]
        complexed with alt, nit
    35. Domain for 1w8l:
    36. Domain for 1w8m:
    37. Domain for 1w8v:
    38. Domain for 2cpl:
    39. Domain for 2cyh:
    40. Domains for 2rma:
      1. 565111Domain d2rmaa_: 2rma A: [27435]
      2. 565112Domain d2rmac_: 2rma C: [27436]
      3. 565113Domain d2rmae_: 2rma E: [27437]
      4. 565114Domain d2rmag_: 2rma G: [27438]
      5. 565115Domain d2rmai_: 2rma I: [27439]
      6. 565116Domain d2rmak_: 2rma K: [27440]
      7. 565117Domain d2rmam_: 2rma M: [27441]
      8. 565118Domain d2rmao_: 2rma O: [27442]
      9. 565119Domain d2rmaq_: 2rma Q: [27443]
      10. 565120Domain d2rmas_: 2rma S: [27444]
        complexed with aba
    41. Domains for 2rmb:
      1. 565122Domain d2rmba_: 2rmb A: [27446]
      2. 565123Domain d2rmbc_: 2rmb C: [27447]
      3. 565124Domain d2rmbe_: 2rmb E: [27448]
      4. 565125Domain d2rmbg_: 2rmb G: [27449]
      5. 565126Domain d2rmbi_: 2rmb I: [27450]
      6. 565127Domain d2rmbk_: 2rmb K: [27451]
      7. 565128Domain d2rmbm_: 2rmb M: [27452]
      8. 565129Domain d2rmbo_: 2rmb O: [27453]
      9. 565130Domain d2rmbq_: 2rmb Q: [27454]
      10. 565131Domain d2rmbs_: 2rmb S: [27455]
        complexed with aba, dmt
    42. Domain for 3cyh:
    43. Domain for 3cys:
    44. Domain for 4cyh:
    45. Domain for 5cyh:
  6. 565170Human (Homo sapiens), variant B [TaxId:9606] [50895] (1 PDB entry)
  7. 565172Mouse (Mus musculus), variant C [TaxId:10090] [50897] (1 PDB entry)
  8. 565177Nematode (Brugia malayi) [TaxId:6279] [50898] (3 PDB entries)
    1. Domain for 1a33:
    2. Domain for 1a58:
    3. Domains for 1c5f:
      1. 565180Domain d1c5fa_: 1c5f A: [27497]
      2. 565181Domain d1c5fc_: 1c5f C: [27498]
      3. 565182Domain d1c5fe_: 1c5f E: [27499]
      4. 565183Domain d1c5fg_: 1c5f G: [27500]
      5. 565184Domain d1c5fi_: 1c5f I: [27501]
      6. 565185Domain d1c5fk_: 1c5f K: [27502]
      7. 565186Domain d1c5fm_: 1c5f M: [27503]
      8. 565187Domain d1c5fo_: 1c5f O: [27504]
  9. 565188Plasmodium falciparum [50900] (2 PDB entries)
    1. Domain for 1qng:
    2. Domains for 1qnh:
      1. 565190Domain d1qnha_: 1qnh A: [27508]
      2. 565191Domain d1qnhb_: 1qnh B: [27509]
        complexed with aba; mutant
  10. 565192Trypanosoma cruzi [TaxId:5693] [117269] (2 PDB entries)
    1. Domains for 1xo7:
      1. 565193Domain d1xo7a_: 1xo7 A: [115694]
      2. 565194Domain d1xo7b_: 1xo7 B: [115695]
      3. 565195Domain d1xo7c_: 1xo7 C: [115696]
      4. 565196Domain d1xo7d_: 1xo7 D: [115697]
        Structural genomics target
    2. Domains for 1xq7:
      1. 565197Domain d1xq7a_: 1xq7 A: [115831]
      2. 565198Domain d1xq7b_: 1xq7 B: [115832]
      3. 565199Domain d1xq7c_: 1xq7 C: [115833]
        Structural genomics target
        complexed with aba

More info for Protein Cyclophilin (eukaryotic) from b.62.1.1: Cyclophilin (peptidylprolyl isomerase)

Timeline for Protein Cyclophilin (eukaryotic) from b.62.1.1: Cyclophilin (peptidylprolyl isomerase):