SCOPe 2.07: Family b.55.1.5: Third domain of FERM

Lineage for Family b.55.1.5: Third domain of FERM

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.55: PH domain-like barrel [50728] (3 superfamilies)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (14 families)

5. Family b.55.1.5: Third domain of FERM [50776] (8 proteins)

Proteins:

1. Erythroid membrane protein 4.1R [50781] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50782] (1 PDB entry)

2. Ezrin [82142] (1 species)
   complexed with the icam-2 cytoplasmic peptide, chain B

   • Species Human (Homo sapiens) [TaxId:9606] [82143] (1 PDB entry)

3. Focal adhesion kinase 1 [141432] (1 species)

   • Species Chicken (Gallus gallus) [TaxId:9031] [141433] (2 PDB entries)
     Uniprot Q00944 254-363

4. Merlin [69294] (2 species)
   the neurofibromatosis 2 tumor suppressor protein

   1. Species Human (Homo sapiens) [TaxId:9606] [69295] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [74995] (1 PDB entry)

5. Moesin [50777] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [50778] (3 PDB entries)
      Uniprot P26038 4-297

   2. Species Mouse (Mus musculus) [TaxId:10090] [311105] (1 PDB entry)

6. Radixin [50779] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [50780] (9 PDB entries)

7. Talin [82144] (1 species)

   • Species Chicken (Gallus gallus) [TaxId:9031] [82145] (7 PDB entries)

8. Talin-1 [117261] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [117262] (1 PDB entry)
     Uniprot P26039 209-410

More info for Family b.55.1.5: Third domain of FERM

Timeline for Family b.55.1.5: Third domain of FERM:

• Family b.55.1.5: Third domain of FERM first appeared (with stable ids) in SCOP 1.55
  
• Family b.55.1.5: Third domain of FERM appears in SCOPe 2.06
  
• Family b.55.1.5: Third domain of FERM appears in the current release, SCOPe 2.08