Lineage for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 563841Fold b.55: PH domain-like [50728] (1 superfamily)
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  4. 563842Superfamily b.55.1: PH domain-like [50729] (9 families) (S)
  5. 563991Family b.55.1.2: Phosphotyrosine-binding domain (PTB) [50755] (10 proteins)
    Pfam 00640

Proteins:

  1. 563992Amyloid beta A4 precursor protein-binding family B member 2, Apbb2 [117259] (1 species)
  2. 563995Disabled homolog 1 (Dab1) [89357] (1 species)
  3. 564001Disabled homolog 2 (Dab2) [101830] (1 species)
  4. 564009Docking protein 1, Dok1 [101834] (1 species)
  5. 564015Downstream of tyrosine kinase 5, Dok-5 [101832] (1 species)
  6. 564019FGFR substrate 2 (SNT-1) [117257] (1 species)
  7. 564022Insulin receptor substrate 1, IRS-1 [50758] (1 species)
    duplication: contains two domains of this fold
  8. 564029Numb [50762] (2 species)
    1. 564030Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [50763] (2 PDB entries)
    2. 564033Species Mouse (Mus musculus) [TaxId:10090] [117256] (1 PDB entry)
  9. 564035Shc adaptor protein [50760] (1 species)
  10. 564040X11 [50756] (1 species)

More info for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

Timeline for Family b.55.1.2: Phosphotyrosine-binding domain (PTB):