SCOP 1.69: Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

Lineage for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.55: PH domain-like [50728] (1 superfamily)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (9 families)

5. Family b.55.1.2: Phosphotyrosine-binding domain (PTB) [50755] (8 proteins)

Proteins:

1. Disabled homolog 1 (Dab1) [89357] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [89358] (3 PDB entries)

2. Disabled homolog 2 (Dab2) [101830] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [101831] (2 PDB entries)

3. Docking protein 1, Dok1 [101834] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [101835] (2 PDB entries)

4. Downstream of tyrosine kinase 5, Dok-5 [101832] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101833] (1 PDB entry)

5. Insulin receptor substrate 1, IRS-1 [50758] (1 species)
   duplication: contains two domains of this fold

   • Species Human (Homo sapiens) [TaxId:9606] [50759] (2 PDB entries)

6. Numb [50762] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [50763] (2 PDB entries)

7. Shc adaptor protein [50760] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50761] (3 PDB entries)

8. X11 [50756] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50757] (2 PDB entries)

More info for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

Timeline for Family b.55.1.2: Phosphotyrosine-binding domain (PTB):

• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) first appeared (with stable ids) in SCOP 1.55
  
• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) appears in SCOP 1.67
  
• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) appears in SCOP 1.71
  
• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) appears in the current release, SCOPe 2.08