Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2061576Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  4. 2061577Superfamily b.55.1: PH domain-like [50729] (14 families) (S)
  5. 2061578Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (48 protein domains)
    Pfam PF00169
  6. 2061598Protein Bruton's tyrosine kinase [50738] (1 species)
    contains Btk zinc-binding motif
  7. 2061599Species Human (Homo sapiens) [TaxId:9606] [50739] (3 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1b55:
    1. 2061604Domain d1b55a_: 1b55 A: [26963]
      complexed with 4ip, zn
    2. 2061605Domain d1b55b_: 1b55 B: [26964]
      complexed with 4ip, zn
  2. Domain(s) for 1btk:
    1. 2061600Domain d1btka_: 1btk A: [26959]
      complexed with na, zn; mutant
    2. 2061601Domain d1btkb_: 1btk B: [26960]
      complexed with na, zn; mutant
  3. Domain(s) for 1bwn:
    1. 2061602Domain d1bwna_: 1bwn A: [26961]
      complexed with 4ip, zn; mutant
    2. 2061603Domain d1bwnb_: 1bwn B: [26962]
      complexed with 4ip, zn; mutant

More info for Species Human (Homo sapiens) [TaxId:9606] from b.55.1.1 Bruton's tyrosine kinase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.55.1.1 Bruton's tyrosine kinase: