Lineage for Family b.55.1.1: Pleckstrin-homology domain (PH domain)

  1. Root: SCOP 1.63
  2. 218896Class b: All beta proteins [48724] (119 folds)
  3. 232087Fold b.55: PH domain-like [50728] (1 superfamily)
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  4. 232088Superfamily b.55.1: PH domain-like [50729] (6 families) (S)
  5. 232089Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (14 proteins)

Proteins:

  1. 232090beta-spectrin [50733] (2 species)
    1. 232091Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [50735] (1 PDB entry)
    2. 232093Species Mouse (Mus musculus), brain [TaxId:10090] [50734] (2 PDB entries)
  2. 232096Bruton's tyrosine kinase [50738] (1 species)
    contains Btk zinc-binding motif
  3. 232104Dbl's big sister, Dbs [74989] (1 species)
  4. 232114Dual adaptor of phosphotyrosine and 3-phosphoinositides DAPP1/PHISH [50749] (1 species)
  5. 232118Dynamin [50736] (1 species)
  6. 232124G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1) [50747] (1 species)
  7. 232127GEF of intersectin [74991] (1 species)
  8. 232131GEF of TIAM1 (T-Lymphoma invasion and metastasis indusing protein 1) [50745] (1 species)
  9. 232137Grp1 [50751] (1 species)
    ARF1 Guanine nucleotide exchange factor and integrin binding protein homolog
  10. 232145Phospholipase C delta-1 [50731] (1 species)
  11. 232148Pleckstrin, N-terminal domain [50740] (1 species)
  12. 232151Son of sevenless-1 (sos-1) [50742] (2 species)
    1. 232152Species Human (Homo sapiens) [TaxId:9606] [50744] (2 PDB entries)
    2. 232155Species Mouse (Mus musculus) [TaxId:10090] [50743] (1 PDB entry)
  13. 232157Tapp1 [74993] (1 species)
  14. 232160UNC-89 [50753] (1 species)

More info for Family b.55.1.1: Pleckstrin-homology domain (PH domain)

Timeline for Family b.55.1.1: Pleckstrin-homology domain (PH domain):