Lineage for Protein: Plasmepsin (a hemoglobin-degrading enzyme)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2067626Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2067627Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2069061Family b.50.1.2: Pepsin-like [50646] (11 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 2070258Protein Plasmepsin (a hemoglobin-degrading enzyme) [50673] (3 species)

Species:

  1. 2070259Plasmodium falciparum, plasmepsin II [TaxId:5833] [50674] (22 PDB entries)
    1. Domain for 1lee:
    2. Domain for 1lf2:
    3. Domain for 1lf3:
    4. Domain for 1lf4:
    5. Domains for 1m43:
      1. 2070282Domain d1m43a_: 1m43 A: [74438]
      2. 2070283Domain d1m43b_: 1m43 B: [74439]
    6. Domains for 1me6:
      1. 2070291Domain d1me6a_: 1me6 A: [91247]
        complexed with ivs
      2. 2070292Domain d1me6b_: 1me6 B: [91248]
        complexed with ivs
    7. Domains for 1pfz:
      1. 2070264Domain d1pfza_: 1pfz A: [26881]
        complexed with gol
      2. 2070265Domain d1pfzb_: 1pfz B: [26882]
        complexed with gol
      3. 2070266Domain d1pfzc_: 1pfz C: [26883]
        complexed with gol
      4. 2070267Domain d1pfzd_: 1pfz D: [26884]
        complexed with gol
    8. Domains for 1sme:
      1. 2070285Domain d1smea_: 1sme A: [26885]
      2. 2070286Domain d1smeb_: 1sme B: [26886]
    9. Domains for 1w6h:
      1. 2070278Domain d1w6ha_: 1w6h A: [120663]
        automated match to d1leea_
        complexed with tit
      2. 2070279Domain d1w6hb_: 1w6h B: [120664]
        automated match to d1leea_
        complexed with tit
    10. Domains for 1w6i:
      1. 2070289Domain d1w6ia_: 1w6i A: [120665]
        automated match to d1leea_
      2. 2070290Domain d1w6ic_: 1w6i C: [120666]
        automated match to d1leea_
    11. Domains for 1xdh:
      1. 2070262Domain d1xdha_: 1xdh A: [121870]
        automated match to d1leea_
      2. 2070263Domain d1xdhb_: 1xdh B: [121871]
        automated match to d1leea_
    12. Domains for 1xe5:
      1. 2070280Domain d1xe5a_: 1xe5 A: [121906]
        automated match to d1leea_
        complexed with 5fe
      2. 2070281Domain d1xe5b_: 1xe5 B: [121907]
        automated match to d1leea_
        complexed with 5fe
    13. Domains for 1xe6:
      1. 2070298Domain d1xe6a_: 1xe6 A: [121908]
        automated match to d1leea_
        complexed with 5fp
      2. 2070299Domain d1xe6b_: 1xe6 B: [121909]
        automated match to d1leea_
        complexed with 5fp
    14. Domain for 2bju:
    15. Domain for 2igx:
    16. Domains for 2igy:
      1. 2070287Domain d2igya_: 2igy A: [137405]
        automated match to d1leea_
        complexed with a2t
      2. 2070288Domain d2igyb_: 2igy B: [137406]
        automated match to d1leea_
        complexed with a2t
    17. Domains for 2r9b:
      1. 2070293Domain d2r9ba_: 2r9b A: [151764]
        automated match to d1leea_
      2. 2070294Domain d2r9bb_: 2r9b B: [151765]
        automated match to d1leea_
    18. Domain for 3f9q:
    19. Domains for 4cku:
      1. 2070270Domain d4ckua_: 4cku A: [256625]
        automated match to d1leea_
        complexed with p2f
      2. 2070271Domain d4ckub_: 4cku B: [256626]
        automated match to d1leea_
        complexed with p2f
      3. 2070272Domain d4ckuc_: 4cku C: [256628]
        automated match to d1leea_
        complexed with p2f
      4. 2070273Domain d4ckud_: 4cku D: [256627]
        automated match to d1leea_
        complexed with p2f
      5. 2070274Domain d4ckue_: 4cku E: [256630]
        automated match to d1leea_
        complexed with p2f
      6. 2070275Domain d4ckuf_: 4cku F: [256629]
        automated match to d1leea_
        complexed with p2f
    20. Domains for 4y6m:
      1. 2070295Domain d4y6ma_: 4y6m A: [279859]
        automated match to d1leea_
        complexed with 48q, gol
      2. 2070296Domain d4y6mb_: 4y6m B: [279860]
        automated match to d1leea_
        complexed with 48q, gol
      3. 2070297Domain d4y6mc_: 4y6m C: [279861]
        automated match to d1leea_
        complexed with 48q, gol
    21. Domains for 4z22:
      1. 2070300Domain d4z22a_: 4z22 A: [280549]
        automated match to d1leea_
        complexed with 4kg
      2. 2070301Domain d4z22b_: 4z22 B: [280556]
        automated match to d1leea_
        complexed with 4kg
    22. Domain for 5bwy:
  2. 2070303Plasmodium falciparum, plasmepsin IV [TaxId:5833] [74986] (2 PDB entries)
    1. Domains for 1jgf:
      1. 2070304Domain d1jgfa_: 1jgf A: [302574]
        automated match to d1ls5a_
        complexed with ihn
      2. 2070305Domain d1jgfb_: 1jgf B: [302575]
        automated match to d1ls5a_
        complexed with ihn
    2. Domains for 1ls5:
      1. 2070306Domain d1ls5a_: 1ls5 A: [74240]
      2. 2070307Domain d1ls5b_: 1ls5 B: [74241]
  3. 2070308Plasmodium vivax [TaxId:5855] [50675] (2 PDB entries)
    1. Domains for 1miq:
      1. 2070311Domain d1miqa_: 1miq A: [79151]
        proenzyme
      2. 2070312Domain d1miqb_: 1miq B: [79152]
        proenzyme
    2. Domains for 1qs8:
      1. 2070309Domain d1qs8a_: 1qs8 A: [26887]
        complexed with act
      2. 2070310Domain d1qs8b_: 1qs8 B: [26888]
        complexed with act

More info for Protein Plasmepsin (a hemoglobin-degrading enzyme) from b.50.1.2: Pepsin-like

Timeline for Protein Plasmepsin (a hemoglobin-degrading enzyme) from b.50.1.2: Pepsin-like: