Lineage for Protein: Plasmepsin (a hemoglobin-degrading enzyme)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 671907Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 671908Superfamily b.50.1: Acid proteases [50630] (2 families) (S)
  5. 672460Family b.50.1.2: Pepsin-like [50646] (10 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 672681Protein Plasmepsin (a hemoglobin-degrading enzyme) [50673] (3 species)

Species:

  1. 672682Plasmodium falciparum, plasmepsin II [TaxId:5833] [50674] (16 PDB entries)
    1. Domain for 1lee:
    2. Domain for 1lf2:
    3. Domain for 1lf3:
    4. Domain for 1lf4:
    5. Domains for 1m43:
      1. 672696Domain d1m43a_: 1m43 A: [74438]
      2. 672697Domain d1m43b_: 1m43 B: [74439]
        complexed with ihn; mutant
    6. Domains for 1me6:
      1. 672705Domain d1me6a_: 1me6 A: [91247]
      2. 672706Domain d1me6b_: 1me6 B: [91248]
        complexed with ivs
    7. Domains for 1pfz:
      1. 672688Domain d1pfza_: 1pfz A: [26881]
      2. 672689Domain d1pfzb_: 1pfz B: [26882]
      3. 672690Domain d1pfzc_: 1pfz C: [26883]
      4. 672691Domain d1pfzd_: 1pfz D: [26884]
        complexed with gol; mutant
    8. Domains for 1sme:
      1. 672701Domain d1smea_: 1sme A: [26885]
      2. 672702Domain d1smeb_: 1sme B: [26886]
        complexed with ihn
    9. Domains for 1w6h:
      1. 672694Domain d1w6ha1: 1w6h A:1-329 [120663]
        automatically matched to d1lf3a_
        complexed with tit
      2. 672695Domain d1w6hb1: 1w6h B:1-329 [120664]
        automatically matched to d1lf3a_
        complexed with tit
    10. Domains for 1w6i:
      1. 672707Domain d1w6ia1: 1w6i A:1-329 [120665]
        automatically matched to d1lf3a_
        complexed with ihn
      2. 672708Domain d1w6ic1: 1w6i C:1-329 [120666]
        automatically matched to d1lf3a_
        complexed with ihn
    11. Domains for 1xdh:
      1. 672685Domain d1xdha1: 1xdh A:1-329 [121870]
        automatically matched to d1lf3a_
        complexed with ihn
      2. 672686Domain d1xdhb1: 1xdh B:1-329 [121871]
        automatically matched to d1lf3a_
        complexed with ihn
    12. Domains for 1xe5:
      1. 672698Domain d1xe5a1: 1xe5 A:1-329 [121906]
        automatically matched to d1lf3a_
        complexed with 5fe
      2. 672699Domain d1xe5b1: 1xe5 B:1-329 [121907]
        automatically matched to d1lf3a_
        complexed with 5fe
    13. Domains for 1xe6:
      1. 672709Domain d1xe6a1: 1xe6 A:1-329 [121908]
        automatically matched to d1lf3a_
        complexed with 5fp
      2. 672710Domain d1xe6b1: 1xe6 B:1-329 [121909]
        automatically matched to d1lf3a_
        complexed with 5fp
    14. Domain for 2bju:
    15. Domain for 2igx:
    16. Domains for 2igy:
      1. 672703Domain d2igya1: 2igy A:1-329 [137405]
        automatically matched to d1lf3a_
        complexed with a2t
      2. 672704Domain d2igyb1: 2igy B:1-329 [137406]
        automatically matched to d1lf3a_
        complexed with a2t
  2. 672711Plasmodium falciparum, plasmepsin IV [TaxId:5833] [74986] (1 PDB entry)
  3. 672714Plasmodium vivax [TaxId:5855] [50675] (2 PDB entries)
    1. Domains for 1miq:
      1. 672717Domain d1miqa_: 1miq A: [79151]
      2. 672718Domain d1miqb_: 1miq B: [79152]
        proenzyme
    2. Domains for 1qs8:
      1. 672715Domain d1qs8a_: 1qs8 A: [26887]
      2. 672716Domain d1qs8b_: 1qs8 B: [26888]
        complexed with act, iva, sta

More info for Protein Plasmepsin (a hemoglobin-degrading enzyme) from b.50.1.2: Pepsin-like

Timeline for Protein Plasmepsin (a hemoglobin-degrading enzyme) from b.50.1.2: Pepsin-like: