| Class b: All beta proteins [48724] (165 folds) |
| Fold b.50: Acid proteases [50629] (1 superfamily) barrel, closed; n=6, S=10, complex topology |
Superfamily b.50.1: Acid proteases [50630] (2 families) ![]() |
| Family b.50.1.2: Pepsin-like [50646] (10 proteins) duplication: consists of two similar barrel domains N-terminal: barrel, partly opened; n*=6, S*=10 |
| Protein Plasmepsin (a hemoglobin-degrading enzyme) [50673] (3 species) |
| Plasmodium falciparum, plasmepsin II [TaxId:5833] [50674] (16 PDB entries) |
| Domain d1leea_: 1lee A: [77908] complexed with r36 |
| Domain d1lf2a_: 1lf2 A: [77914] complexed with r37 |
| Domain d1lf3a_: 1lf3 A: [77915] complexed with eh5 |
| Domain d1lf4a_: 1lf4 A: [77916] |
| Domain d1m43a_: 1m43 A: [74438] |
| Domain d1m43b_: 1m43 B: [74439] complexed with ihn; mutant |
| Domain d1me6a_: 1me6 A: [91247] |
| Domain d1me6b_: 1me6 B: [91248] complexed with ivs |
| Domain d1pfza_: 1pfz A: [26881] |
| Domain d1pfzb_: 1pfz B: [26882] |
| Domain d1pfzc_: 1pfz C: [26883] |
| Domain d1pfzd_: 1pfz D: [26884] complexed with gol; mutant |
| Domain d1smea_: 1sme A: [26885] |
| Domain d1smeb_: 1sme B: [26886] complexed with ihn |
| Domain d1w6ha1: 1w6h A:1-329 [120663] automatically matched to d1lf3a_ complexed with tit |
| Domain d1w6hb1: 1w6h B:1-329 [120664] automatically matched to d1lf3a_ complexed with tit |
| Domain d1w6ia1: 1w6i A:1-329 [120665] automatically matched to d1lf3a_ complexed with ihn |
| Domain d1w6ic1: 1w6i C:1-329 [120666] automatically matched to d1lf3a_ complexed with ihn |
| Domain d1xdha1: 1xdh A:1-329 [121870] automatically matched to d1lf3a_ complexed with ihn |
| Domain d1xdhb1: 1xdh B:1-329 [121871] automatically matched to d1lf3a_ complexed with ihn |
| Domain d1xe5a1: 1xe5 A:1-329 [121906] automatically matched to d1lf3a_ complexed with 5fe |
| Domain d1xe5b1: 1xe5 B:1-329 [121907] automatically matched to d1lf3a_ complexed with 5fe |
| Domain d1xe6a1: 1xe6 A:1-329 [121908] automatically matched to d1lf3a_ complexed with 5fp |
| Domain d1xe6b1: 1xe6 B:1-329 [121909] automatically matched to d1lf3a_ complexed with 5fp |
| Domain d2bjua1: 2bju A:1-329 [128633] automatically matched to d1lf3a_ complexed with ih4 |
| Domain d2igxa1: 2igx A:1-329 [137404] automatically matched to d1lf3a_ complexed with a1t |
| Domain d2igya1: 2igy A:1-329 [137405] automatically matched to d1lf3a_ complexed with a2t |
| Domain d2igyb1: 2igy B:1-329 [137406] automatically matched to d1lf3a_ complexed with a2t |
| Plasmodium falciparum, plasmepsin IV [TaxId:5833] [74986] (1 PDB entry) |
| Domain d1ls5a_: 1ls5 A: [74240] |
| Domain d1ls5b_: 1ls5 B: [74241] complexed with ihn |
| Plasmodium vivax [TaxId:5855] [50675] (2 PDB entries) |
| Domain d1miqa_: 1miq A: [79151] |
| Domain d1miqb_: 1miq B: [79152] proenzyme |
| Domain d1qs8a_: 1qs8 A: [26887] |
| Domain d1qs8b_: 1qs8 B: [26888] complexed with act, iva, sta |
Timeline for Protein Plasmepsin (a hemoglobin-degrading enzyme) from b.50.1.2: Pepsin-like: