Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 671907Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 671908Superfamily b.50.1: Acid proteases [50630] (2 families) (S)
  5. 672460Family b.50.1.2: Pepsin-like [50646] (10 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 672515Protein beta-secretase (memapsin) [50671] (1 species)
  7. 672516Species Human (Homo sapiens) [TaxId:9606] [50672] (30 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1fkn:
    1. 672518Domain d1fkna_: 1fkn A: [26879]
    2. 672519Domain d1fknb_: 1fkn B: [26880]
      complexed with alq, lol
  2. Domain(s) for 1m4h:
    1. 672544Domain d1m4ha_: 1m4h A: [74455]
    2. 672545Domain d1m4hb_: 1m4h B: [74456]
      complexed with alq, lol
  3. Domain(s) for 1sgz:
    1. 672529Domain d1sgza_: 1sgz A: [98872]
    2. 672530Domain d1sgzb_: 1sgz B: [98873]
    3. 672531Domain d1sgzc_: 1sgz C: [98874]
    4. 672532Domain d1sgzd_: 1sgz D: [98875]
  4. Domain(s) for 1tqf:
  5. Domain(s) for 1w50:
  6. Domain(s) for 1w51:
  7. Domain(s) for 1xn2:
    1. 672521Domain d1xn2a1: 1xn2 A:45P-385 [122178]
      automatically matched to d1fkna_
      complexed with alq
    2. 672522Domain d1xn2b1: 1xn2 B:45P-385 [122179]
      automatically matched to d1fkna_
      complexed with alq
    3. 672523Domain d1xn2c1: 1xn2 C:45P-385 [122180]
      automatically matched to d1fkna_
      complexed with alq
    4. 672524Domain d1xn2d1: 1xn2 D:45P-385 [122181]
      automatically matched to d1fkna_
      complexed with alq
  8. Domain(s) for 1xn3:
    1. 672534Domain d1xn3a1: 1xn3 A:45P-385 [122182]
      automatically matched to d1fkna_
      complexed with sta
    2. 672535Domain d1xn3b1: 1xn3 B:45P-385 [122183]
      automatically matched to d1fkna_
      complexed with sta
    3. 672536Domain d1xn3c1: 1xn3 C:45P-385 [122184]
      automatically matched to d1fkna_
      complexed with sta
    4. 672537Domain d1xn3d1: 1xn3 D:45P-385 [122185]
      automatically matched to d1fkna_
      complexed with sta
  9. Domain(s) for 1xs7:
  10. Domain(s) for 1ym2:
    1. 672538Domain d1ym2a1: 1ym2 A:-2-385 [123679]
      automatically matched to d1fkna_
      complexed with aua
    2. 672539Domain d1ym2b1: 1ym2 B:-2-385 [123680]
      automatically matched to d1fkna_
      complexed with aua
    3. 672540Domain d1ym2c1: 1ym2 C:-2-385 [123681]
      automatically matched to d1fkna_
      complexed with aua
  11. Domain(s) for 1ym4:
    1. 672556Domain d1ym4a1: 1ym4 A:-3-385 [123682]
      automatically matched to d1fkna_
      complexed with amk
    2. 672557Domain d1ym4b1: 1ym4 B:-2-385 [123683]
      automatically matched to d1fkna_
      complexed with amk
    3. 672558Domain d1ym4c1: 1ym4 C:-3-385 [123684]
      automatically matched to d1fkna_
      complexed with amk
  12. Domain(s) for 2f3e:
    1. 672541Domain d2f3ea1: 2f3e A:46P-385 [132864]
      automatically matched to d1fkna_
      complexed with axq
    2. 672542Domain d2f3eb1: 2f3e B:46P-385 [132865]
      automatically matched to d1fkna_
      complexed with axq
    3. 672543Domain d2f3ec1: 2f3e C:46P-385 [132866]
      automatically matched to d1fkna_
      complexed with axq
  13. Domain(s) for 2f3f:
    1. 672571Domain d2f3fa1: 2f3f A:46P-385 [132867]
      automatically matched to d1fkna_
      complexed with axf
    2. 672572Domain d2f3fb1: 2f3f B:46P-385 [132868]
      automatically matched to d1fkna_
      complexed with axf
    3. 672573Domain d2f3fc1: 2f3f C:46P-385 [132869]
      automatically matched to d1fkna_
      complexed with axf
  14. Domain(s) for 2fdp:
    1. 672565Domain d2fdpa1: 2fdp A:46P-385 [133316]
      automatically matched to d1fkna_
      complexed with frp
    2. 672566Domain d2fdpb1: 2fdp B:46P-385 [133317]
      automatically matched to d1fkna_
      complexed with frp
    3. 672567Domain d2fdpc1: 2fdp C:46P-385 [133318]
      automatically matched to d1fkna_
      complexed with frp
  15. Domain(s) for 2g94:
    1. 672525Domain d2g94a1: 2g94 A:45P-385 [134790]
      automatically matched to d1fkna_
      complexed with zpq
    2. 672526Domain d2g94b1: 2g94 B:45P-385 [134791]
      automatically matched to d1fkna_
      complexed with zpq
    3. 672527Domain d2g94c1: 2g94 C:45P-385 [134792]
      automatically matched to d1fkna_
      complexed with zpq
    4. 672528Domain d2g94d1: 2g94 D:45P-385 [134793]
      automatically matched to d1fkna_
      complexed with zpq
  16. Domain(s) for 2hiz:
    1. 672559Domain d2hiza1: 2hiz A:61P-385 [136533]
      automatically matched to d1fkna_
      complexed with lij, po4
    2. 672560Domain d2hizb1: 2hiz B:61P-385 [136534]
      automatically matched to d1fkna_
      complexed with lij, po4
    3. 672561Domain d2hizc1: 2hiz C:61P-385 [136535]
      automatically matched to d1fkna_
      complexed with lij, po4
  17. Domain(s) for 2hm1:
  18. Domain(s) for 2iqg:
  19. Domain(s) for 2of0:
  20. Domain(s) for 2ohk:
  21. Domain(s) for 2ohl:
  22. Domain(s) for 2ohm:
  23. Domain(s) for 2ohn:
  24. Domain(s) for 2ohp:
  25. Domain(s) for 2ohq:
  26. Domain(s) for 2ohr:
  27. Domain(s) for 2ohs:
  28. Domain(s) for 2oht:
  29. Domain(s) for 2ohu:
  30. Domain(s) for 2p83:
    1. 672562Domain d2p83a1: 2p83 A:61P-385 [139519]
      automatically matched to d1fkna_
      complexed with mr0, po4
    2. 672563Domain d2p83b1: 2p83 B:61P-385 [139520]
      automatically matched to d1fkna_
      complexed with mr0, po4
    3. 672564Domain d2p83c1: 2p83 C:61P-385 [139521]
      automatically matched to d1fkna_
      complexed with mr0, po4

More info for Species Human (Homo sapiens) [TaxId:9606] from b.50.1.2 beta-secretase (memapsin)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.50.1.2 beta-secretase (memapsin):