Lineage for Protein: Pepsin(ogen)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2060177Family b.50.1.2: Pepsin-like [50646] (11 protein domains)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 2060854Protein Pepsin(ogen) [50658] (4 species)

Species:

  1. 2060855Atlantic cod (Gadus morhua) [TaxId:8049] [50662] (1 PDB entry)
  2. 2060857Human (Homo sapiens), isoform 3A [TaxId:9606] [50660] (5 PDB entries)
    1. Domain for 1flh:
    2. Domain for 1psn:
    3. Domain for 1pso:
    4. Domain for 1qrp:
    5. Domain for 3utl:
  3. 2060863Human (Homo sapiens), progastricsin (pepsinogen C) [TaxId:9606] [50661] (2 PDB entries)
    1. Domains for 1avf:
      1. 2060865Domain d1avf.1: 1avf P:,A: [26853]
        activation intermediate 2
        complexed with na
      2. 2060866Domain d1avf.2: 1avf Q:,J: [26854]
        activation intermediate 2
        complexed with na
    2. Domain for 1htr:
  4. 2060867Pig (Sus scrofa) [TaxId:9823] [50659] (8 PDB entries)
    1. Domain for 1f34:
    2. Domains for 1psa:
      1. 2060873Domain d1psaa_: 1psa A: [26846]
        complexed with 0zl
      2. 2060874Domain d1psab_: 1psa B: [26847]
        complexed with 0zl
    3. Domain for 1yx9:
    4. Domain for 2psg:
    5. Domain for 3pep:
    6. Domain for 3psg:
    7. Domain for 4pep:
    8. Domain for 5pep:

More info for Protein Pepsin(ogen) from b.50.1.2: Pepsin-like

Timeline for Protein Pepsin(ogen) from b.50.1.2: Pepsin-like: