SCOP 1.71: Protein: Human immunodeficiency virus type 2 (HIV-2) protease

Lineage for Protein: Human immunodeficiency virus type 2 (HIV-2) protease

Root: SCOP 1.71
Class b: All beta proteins [48724] (149 folds)
Fold b.50: Acid proteases [50629] (1 superfamily)
barrel, closed; n=6, S=10, complex topology
Superfamily b.50.1: Acid proteases [50630] (2 families)
Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
dimer of identical mono-domain chains, each containing (6,10) barrel
Protein Human immunodeficiency virus type 2 (HIV-2) protease [50634] (1 species)

Species:

Human immunodeficiency virus type 2 [TaxId:11709] [50635] (15 PDB entries)
1. Domains for 1hii:
  1. Domain d1hiia_: 1hii A: [26723]
  2. Domain d1hiib_: 1hii B: [26724]
    complexed with c20, so4
2. Domains for 1hsi:
  1. Domain d1hsia_: 1hsi A: [26737]
  2. Domain d1hsib_: 1hsi B: [26738]
3. Domains for 1ida:
  1. Domain d1idaa_: 1ida A: [26715]
  2. Domain d1idab_: 1ida B: [26716]
    complexed with hpb, ppl, py2, qnd
4. Domains for 1idb:
  1. Domain d1idba_: 1idb A: [26725]
  2. Domain d1idbb_: 1idb B: [26726]
    complexed with dba, phm, ppl, spy
5. Domains for 1ivp:
  1. Domain d1ivpa_: 1ivp A: [26743]
  2. Domain d1ivpb_: 1ivp B: [26744]
    complexed with apy, cav, noa; mutant
6. Domains for 1ivq:
  1. Domain d1ivqa_: 1ivq A: [26741]
  2. Domain d1ivqb_: 1ivq B: [26742]
    complexed with cpv, npt, qnc; mutant
7. Domains for 1jld:
  1. Domain d1jlda_: 1jld A: [26739]
  2. Domain d1jldb_: 1jld B: [26740]
    complexed with phm, qnc, rhs
8. Domains for 2hpe:
  1. Domain d2hpea_: 2hpe A: [26717]
  2. Domain d2hpeb_: 2hpe B: [26718]
    mutant
9. Domains for 2hpf:
  1. Domain d2hpfa_: 2hpf A: [26745]
  2. Domain d2hpfb_: 2hpf B: [26746]
    mutant
10. Domains for 2mip:
  1. Domain d2mipa_: 2mip A: [26731]
  2. Domain d2mipb_: 2mip B: [26732]
  3. Domain d2mipc_: 2mip C: [26733]
  4. Domain d2mipd_: 2mip D: [26734]
    complexed with nh2
11. Domains for 3upj:
  1. Domain d3upja_: 3upj A: [26735]
  2. Domain d3upjb_: 3upj B: [26736]
    complexed with u03; mutant
12. Domains for 4upj:
  1. Domain d4upja_: 4upj A: [26719]
  2. Domain d4upjb_: 4upj B: [26720]
    complexed with u04; mutant
13. Domains for 5upj:
  1. Domain d5upja_: 5upj A: [26729]
  2. Domain d5upjb_: 5upj B: [26730]
    complexed with uin; mutant
14. Domains for 6upj:
  1. Domain d6upja_: 6upj A: [26727]
  2. Domain d6upjb_: 6upj B: [26728]
    complexed with niu; mutant
15. Domains for 7upj:
  1. Domain d7upja_: 7upj A: [26721]
  2. Domain d7upjb_: 7upj B: [26722]
    complexed with inu

More info for Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin)

Timeline for Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin):

Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin) first appeared (with stable ids) in SCOP 1.55
Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin) appears in SCOP 1.69
Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin) appears in SCOP 1.73
Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin) appears in the current release, SCOPe 2.08