Lineage for Protein: Human immunodeficiency virus type 2 (HIV-2) protease

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2058816Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2059984Protein Human immunodeficiency virus type 2 (HIV-2) protease [50634] (2 species)

Species:

  1. 2059985Human immunodeficiency virus type 2 (isolate rod) [TaxId:11720] [187235] (3 PDB entries)
    1. Domains for 3ebz:
      1. 2059988Domain d3ebza_: 3ebz A: [158088]
        automated match to d1hiia_
        complexed with 017, cl, imd, na, zn
      2. 2059989Domain d3ebzb_: 3ebz B: [158089]
        automated match to d1hiia_
        complexed with 017, cl, imd, na, zn
    2. Domains for 3ec0:
      1. 2059990Domain d3ec0a_: 3ec0 A: [158090]
        automated match to d1hiia_
        complexed with cl, grl, imd, na, zn
      2. 2059991Domain d3ec0b_: 3ec0 B: [158091]
        automated match to d1hiia_
        complexed with cl, grl, imd, na, zn
    3. Domains for 3ecg:
      1. 2059986Domain d3ecga_: 3ecg A: [158098]
        automated match to d1hiia_
        complexed with 065, cl, imd, na, zn
      2. 2059987Domain d3ecgb_: 3ecg B: [158099]
        automated match to d1hiia_
        complexed with 065, cl, imd, na, zn
  2. 2059992Human immunodeficiency virus type 2 [TaxId:11709] [50635] (15 PDB entries)
    1. Domains for 1hii:
      1. 2060001Domain d1hiia_: 1hii A: [26723]
        complexed with c20, so4
      2. 2060002Domain d1hiib_: 1hii B: [26724]
        complexed with c20, so4
    2. Domains for 1hsi:
      1. 2060015Domain d1hsia_: 1hsi A: [26737]
      2. 2060016Domain d1hsib_: 1hsi B: [26738]
    3. Domains for 1ida:
      1. 2059993Domain d1idaa_: 1ida A: [26715]
        complexed with 0po
      2. 2059994Domain d1idab_: 1ida B: [26716]
        complexed with 0po
    4. Domains for 1idb:
      1. 2060005Domain d1idba_: 1idb A: [26725]
        complexed with 0do
      2. 2060006Domain d1idbb_: 1idb B: [26726]
        complexed with 0do
    5. Domains for 1ivp:
      1. 2060021Domain d1ivpa_: 1ivp A: [26743]
        complexed with 1zk
      2. 2060022Domain d1ivpb_: 1ivp B: [26744]
        complexed with 1zk
    6. Domains for 1ivq:
      1. 2060019Domain d1ivqa_: 1ivq A: [26741]
        complexed with 0px
      2. 2060020Domain d1ivqb_: 1ivq B: [26742]
        complexed with 0px
    7. Domains for 1jld:
      1. 2060017Domain d1jlda_: 1jld A: [26739]
        complexed with 0pp
      2. 2060018Domain d1jldb_: 1jld B: [26740]
        complexed with 0pp
    8. Domains for 2hpe:
      1. 2059995Domain d2hpea_: 2hpe A: [26717]
      2. 2059996Domain d2hpeb_: 2hpe B: [26718]
    9. Domains for 2hpf:
      1. 2060023Domain d2hpfa_: 2hpf A: [26745]
      2. 2060024Domain d2hpfb_: 2hpf B: [26746]
    10. Domains for 2mip:
      1. 2060011Domain d2mipa_: 2mip A: [26731]
      2. 2060012Domain d2mipb_: 2mip B: [26732]
      3. 2060013Domain d2mipc_: 2mip C: [26733]
      4. 2060014Domain d2mipd_: 2mip D: [26734]
    11. Domains for 3upj:
      1. 2060009Domain d3upja_: 3upj A: [26735]
        complexed with u03; mutant
      2. 2060010Domain d3upjb_: 3upj B: [26736]
        complexed with u03; mutant
    12. Domains for 4upj:
      1. 2059997Domain d4upja_: 4upj A: [26719]
        complexed with u04; mutant
      2. 2059998Domain d4upjb_: 4upj B: [26720]
        complexed with u04; mutant
    13. Domains for 5upj:
      1. 2060007Domain d5upja_: 5upj A: [26729]
        complexed with uin
      2. 2060008Domain d5upjb_: 5upj B: [26730]
        complexed with uin
    14. Domains for 6upj:
      1. 2060003Domain d6upja_: 6upj A: [26727]
        complexed with niu
      2. 2060004Domain d6upjb_: 6upj B: [26728]
        complexed with niu
    15. Domains for 7upj:
      1. 2059999Domain d7upja_: 7upj A: [26721]
        complexed with inu
      2. 2060000Domain d7upjb_: 7upj B: [26722]
        complexed with inu

More info for Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin)

Timeline for Protein Human immunodeficiency virus type 2 (HIV-2) protease from b.50.1.1: Retroviral protease (retropepsin):