Lineage for Family b.50.1.1: Retroviral protease (retropepsin)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 955287Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 955288Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 955289Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel

Proteins:

  1. 955290EIAV protease [50644] (1 species)
  2. 955294Feline immunodeficiency virus (FIV) protease [50638] (1 species)
  3. 955305Human immunodeficiency virus type 1 protease [50632] (5 species)
    1. 955306Species Hiv-1 m:b_arv2/sf2 [TaxId:11685] [187932] (16 PDB entries)
    2. 955346Species Human immunodeficiency virus type 1 (bh5 isolate) [TaxId:11682] [186950] (7 PDB entries)
    3. 955361Species Human immunodeficiency virus type 1 (isolate z2/cdc-z34 group m subtype d) [TaxId:11683] [189173] (1 PDB entry)
    4. 955364Species Human immunodeficiency virus type 1 lw12.3 isolate [TaxId:82834] [189723] (1 PDB entry)
    5. 955367Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (378 PDB entries)
      Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  4. 956124Human immunodeficiency virus type 2 (HIV-2) protease [50634] (2 species)
    1. 956125Species Human immunodeficiency virus type 2 (isolate rod) [TaxId:11720] [187235] (3 PDB entries)
    2. 956132Species Human immunodeficiency virus type 2 [TaxId:11709] [50635] (15 PDB entries)
  5. 956165Mason-Pfizer monkey virus protease [82131] (1 species)
  6. 956168Myeloblastosis-associated viral protease [50642] (1 species)
  7. 956172Rous sarcoma virus protease [50640] (1 species)
  8. 956178Simian immunodeficiency virus (SIV) protease [50636] (1 species)
  9. 956189automated matches [190433] (10 species)
    not a true protein
    1. 956190Species Feline immunodeficiency virus (isolate petaluma) [TaxId:11674] [187795] (1 PDB entry)
    2. 956192Species Feline immunodeficiency virus [TaxId:11673] [189983] (2 PDB entries)
    3. 956197Species Hiv-1 m:b_arv2/sf2 [TaxId:11685] [188968] (6 PDB entries)
    4. 956212Species Human immunodeficiency virus 1 (z2/cdc-z34 isolate) [TaxId:11683] [189840] (2 PDB entries)
    5. 956217Species Human immunodeficiency virus 1 [TaxId:11676] [187327] (21 PDB entries)
    6. 956258Species Human immunodeficiency virus type 1 (bru isolate) [TaxId:11686] [188980] (4 PDB entries)
    7. 956267Species Human immunodeficiency virus type 1 (z2/cdc-z34 isolate) [TaxId:11683] [189175] (1 PDB entry)
    8. 956270Species Human immunodeficiency virus [TaxId:11686] [189979] (1 PDB entry)
    9. 956273Species Human immunodeficiency virus [TaxId:12721] [188065] (1 PDB entry)
    10. 956275Species Mason-pfizer monkey virus [TaxId:11855] [189736] (1 PDB entry)

More info for Family b.50.1.1: Retroviral protease (retropepsin)

Timeline for Family b.50.1.1: Retroviral protease (retropepsin):