SCOP 1.71: Family b.50.1.1: Retroviral protease (retropepsin)

Lineage for Family b.50.1.1: Retroviral protease (retropepsin)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

Proteins:

1. EIAV protease [50644] (1 species)

   • Species Equine infectious anemia virus [TaxId:11665] [50645] (2 PDB entries)

2. Feline immunodeficiency virus (FIV) protease [50638] (1 species)

   • Species Feline immunodeficiency virus [TaxId:11673] [50639] (7 PDB entries)

3. Human immunodeficiency virus type 1 protease [50632] (1 species)

   • Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (179 PDB entries)

4. Human immunodeficiency virus type 2 (HIV-2) protease [50634] (1 species)

   • Species Human immunodeficiency virus type 2 [TaxId:11709] [50635] (15 PDB entries)

5. Mason-Pfizer monkey virus protease [82131] (1 species)

   • Species Simian retrovirus, SRV-1 [82132] (1 PDB entry)

6. Myeloblastosis-associated viral protease [50642] (1 species)

   • Species Myeloblastosis associated virus [50643] (1 PDB entry)

7. Rous sarcoma virus protease [50640] (1 species)

   • Species Rous sarcoma virus, strain pr-C [TaxId:11886] [50641] (2 PDB entries)

8. Simian immunodeficiency virus (SIV) protease [50636] (1 species)

   • Species Simian immunodeficiency virus, different strains [TaxId:11723] [50637] (14 PDB entries)

More info for Family b.50.1.1: Retroviral protease (retropepsin)

Timeline for Family b.50.1.1: Retroviral protease (retropepsin):

• Family b.50.1.1: Retroviral protease (retropepsin) first appeared (with stable ids) in SCOP 1.55
  
• Family b.50.1.1: Retroviral protease (retropepsin) appears in SCOP 1.69
  
• Family b.50.1.1: Retroviral protease (retropepsin) appears in SCOP 1.73
  
• Family b.50.1.1: Retroviral protease (retropepsin) appears in the current release, SCOPe 2.08