SCOPe 2.07: Superfamily b.50.1: Acid proteases

Lineage for Superfamily b.50.1: Acid proteases

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

Families:

1. b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

2. b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

3. b.50.1.3: LPG0085-like [159190] (1 protein)
   Pfam PF05618; DUF785; single-domain protein similar to one pepsin domain with the conserved catalytic Asp motif (not in a few archaeal members of this Pfam family)

4. b.50.1.0: automated matches [191552] (1 protein)
   not a true family

More info for Superfamily b.50.1: Acid proteases

Timeline for Superfamily b.50.1: Acid proteases:

• Superfamily b.50.1: Acid proteases first appeared (with stable ids) in SCOP 1.55
  
• Superfamily b.50.1: Acid proteases appears in SCOPe 2.06
  
• Superfamily b.50.1: Acid proteases appears in the current release, SCOPe 2.08