SCOP 1.75: Superfamily b.50.1: Acid proteases

Lineage for Superfamily b.50.1: Acid proteases

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (3 families)

Families:

1. b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

2. b.50.1.2: Pepsin-like [50646] (10 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

3. b.50.1.3: LPG0085-like [159190] (1 protein)
   Pfam PF05618; DUF785; single-domain protein similar to one pepsin domain with the conserved catalytic Asp motif (not in a few archaeal members of this Pfam family)

More info for Superfamily b.50.1: Acid proteases

Timeline for Superfamily b.50.1: Acid proteases:

• Superfamily b.50.1: Acid proteases first appeared (with stable ids) in SCOP 1.55
  
• Superfamily b.50.1: Acid proteases appears in SCOP 1.73
  
• Superfamily b.50.1: Acid proteases appears in SCOPe 2.01
  
• Superfamily b.50.1: Acid proteases appears in the current release, SCOPe 2.07