Lineage for Protein: 3C cysteine protease (picornain 3C)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2057856Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 protein domains)
  6. 2057861Protein 3C cysteine protease (picornain 3C) [50604] (9 species)

Species:

  1. 2057862Foot-and-mouth disease virus [TaxId:12110] [159189] (2 PDB entries)
    Uniprot P49303 1657-1755! Uniprot P49303 1657-1857
    1. Domain for 2bhg:
    2. Domain for 2j92:
  2. 2057865Human coxsackievirus a16 [TaxId:31704] [189721] (3 PDB entries)
    1. Domain for 3sj8:
    2. Domain for 3sj9:
    3. Domain for 3sji:
  3. 2057869Human enterovirus 71 [TaxId:39054] [189720] (3 PDB entries)
    1. Domains for 3osy:
      1. 2057879Domain d3osya1: 3osy A:1-181 [214524]
        Other proteins in same PDB: d3osya2, d3osyb2, d3osyc2, d3osyd2, d3osye2
        automated match to d3zvfa_
      2. 2057880Domain d3osyb1: 3osy B:1-181 [214525]
        Other proteins in same PDB: d3osya2, d3osyb2, d3osyc2, d3osyd2, d3osye2
        automated match to d3zvfa_
      3. 2057881Domain d3osyc1: 3osy C:1-181 [214526]
        Other proteins in same PDB: d3osya2, d3osyb2, d3osyc2, d3osyd2, d3osye2
        automated match to d3zvfa_
      4. 2057882Domain d3osyd1: 3osy D:1-181 [214527]
        Other proteins in same PDB: d3osya2, d3osyb2, d3osyc2, d3osyd2, d3osye2
        automated match to d3zvfa_
      5. 2057883Domain d3osye1: 3osy E:1-181 [214528]
        Other proteins in same PDB: d3osya2, d3osyb2, d3osyc2, d3osyd2, d3osye2
        automated match to d3zvfa_
    2. Domain for 3sjk:
    3. Domains for 3sjo:
      1. 2057870Domain d3sjoa_: 3sjo A: [192793]
        automated match to d2vb0a_
        complexed with ag7
      2. 2057871Domain d3sjob_: 3sjo B: [192794]
        automated match to d2vb0a_
        complexed with ag7
      3. 2057872Domain d3sjoc_: 3sjo C: [192796]
        automated match to d2vb0a_
        complexed with ag7
      4. 2057873Domain d3sjod_: 3sjo D: [185431]
        automated match to d1l1na_
        complexed with ag7
      5. 2057874Domain d3sjoe_: 3sjo E: [185432]
        automated match to d1l1na_
        complexed with ag7
      6. 2057875Domain d3sjof_: 3sjo F: [192791]
        automated match to d2vb0a_
        complexed with ag7
      7. 2057876Domain d3sjog_: 3sjo G: [192792]
        automated match to d2vb0a_
        complexed with ag7
      8. 2057877Domain d3sjoh_: 3sjo H: [192795]
        automated match to d2vb0a_
        complexed with ag7
  4. 2057884Human enterovirus b [TaxId:138949] [189732] (3 PDB entries)
    1. Domains for 3q3x:
      1. 2057889Domain d3q3xa1: 3q3x A:1-181 [184201]
        Other proteins in same PDB: d3q3xa2, d3q3xb2
        automated match to d1l1na_
        complexed with gol, mg
      2. 2057890Domain d3q3xb1: 3q3x B:1-180 [192798]
        Other proteins in same PDB: d3q3xa2, d3q3xb2
        automated match to d2vb0a_
        complexed with gol, mg
    2. Domains for 3q3y:
      1. 2057885Domain d3q3ya1: 3q3y A:1-180 [184202]
        Other proteins in same PDB: d3q3ya2, d3q3yb2
        automated match to d1l1na_
        complexed with edo, nh4, pi, xnv
      2. 2057886Domain d3q3yb1: 3q3y B:1-180 [184203]
        Other proteins in same PDB: d3q3ya2, d3q3yb2
        automated match to d1l1na_
        complexed with edo, nh4, pi, xnv
    3. Domains for 3ruo:
      1. 2057887Domain d3ruoa1: 3ruo A:1-182 [185190]
        Other proteins in same PDB: d3ruoa2, d3ruob2
        automated match to d1l1na_
        protein/RNA complex; complexed with ag7, cl, mg
      2. 2057888Domain d3ruob1: 3ruo B:1-180 [185191]
        Other proteins in same PDB: d3ruoa2, d3ruob2
        automated match to d1l1na_
        protein/RNA complex; complexed with ag7, cl, mg
  5. 2057891Human hepatitis a virus hu/northern africa/mbb/1978 [TaxId:12100] [186929] (2 PDB entries)
    1. Domain for 2a4o:
    2. Domain for 2cxv:
  6. 2057894Human hepatitis A virus [TaxId:208726] [50606] (5 PDB entries)
    1. Domains for 1hav:
      1. 2057902Domain d1hava_: 1hav A: [26423]
        complexed with cl
      2. 2057903Domain d1havb_: 1hav B: [26424]
        complexed with cl
    2. Domains for 1qa7:
      1. 2057898Domain d1qa7a_: 1qa7 A: [26425]
        complexed with dms, gol, ivf
      2. 2057899Domain d1qa7b_: 1qa7 B: [26426]
        complexed with dms, gol, ivf
      3. 2057900Domain d1qa7c_: 1qa7 C: [26427]
        complexed with dms, gol, ivf
      4. 2057901Domain d1qa7d_: 1qa7 D: [26428]
        complexed with dms, gol, ivf
    3. Domain for 2h6m:
    4. Domain for 2h9h:
    5. Domain for 2hal:
  7. 2057904Human poliovirus 1 Mahoney [TaxId:12081] [74978] (2 PDB entries)
    1. Domains for 1l1n:
      1. 2057905Domain d1l1na_: 1l1n A: [73476]
      2. 2057906Domain d1l1nb_: 1l1n B: [73477]
    2. Domains for 2ijd:
      1. 2057907Domain d2ijd11: 2ijd 1:1-180 [137474]
        Other proteins in same PDB: d2ijd12, d2ijd22
        automatically matched to d1l1na_
        complexed with so4, zn
      2. 2057908Domain d2ijd21: 2ijd 2:1-180 [137476]
        Other proteins in same PDB: d2ijd12, d2ijd22
        automatically matched to d1l1na_
        complexed with so4, zn
  8. 2057909Human rhinovirus 2 [TaxId:12130] [50605] (3 PDB entries)
    1. Domain for 1cqq:
    2. Domain for 5fx5:
    3. Domain for 5fx6:
  9. 2057911Human rhinovirus sp. [TaxId:169066] [189940] (1 PDB entry)

More info for Protein 3C cysteine protease (picornain 3C) from b.47.1.4: Viral cysteine protease of trypsin fold

Timeline for Protein 3C cysteine protease (picornain 3C) from b.47.1.4: Viral cysteine protease of trypsin fold: