Lineage for Family b.47.1.3: Viral proteases

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 802045Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 802046Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) (S)
  5. 803501Family b.47.1.3: Viral proteases [50596] (4 proteins)
    beta sheet in the first domain is opened rather than forms a barrel

Proteins:

  1. 803502NS3 protease [50600] (4 species)
    1. 803503Species Dengue virus type 2 [TaxId:11060] [50602] (3 PDB entries)
    2. 803508Species Dengue virus [TaxId:12637] [159188] (1 PDB entry)
    3. 803511Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [50601] (14 PDB entries)
      Uniprot P27958 1027-1206,1678-1669
      Uniprot P26662 1029-1202,1677-1689
      Uniprot O36579 1054-1207
    4. 803539Species West nile virus [TaxId:11082] [141386] (2 PDB entries)
      Uniprot P06935 1520-1671
  2. 803542NSP4 proteinase [82128] (1 species)
    minimal fold; contains C-terminal extension
  3. 803548TEV protease (nucleat inclusion protein A, NIA) [82126] (1 species)
  4. 803556Viral capsid protein [50597] (3 species)
    1. 803557Species Semliki forest virus [TaxId:11033] [50599] (2 PDB entries)
    2. 803563Species Sindbis virus [TaxId:11034] [50598] (11 PDB entries)
    3. 803583Species Venezuelan equine encephalitis virus [TaxId:11036] [89347] (2 PDB entries)

More info for Family b.47.1.3: Viral proteases

Timeline for Family b.47.1.3: Viral proteases: