Lineage for Family b.47.1.3: Viral proteases

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 298675Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 298676Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) (S)
  5. 299596Family b.47.1.3: Viral proteases [50596] (4 proteins)
    beta sheet in the first domain is opened rather than forms a barrel

Proteins:

  1. 299597NS3 protease [50600] (2 species)
    1. 299598Species Dengue virus serotype 2 [50602] (2 PDB entries)
    2. 299602Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [50601] (10 PDB entries)
  2. 299622NSP4 proteinase [82128] (1 species)
    minimal fold; contains C-terminal extension
  3. 299628TEV protease (nucleat inclusion protein A, NIA) [82126] (1 species)
  4. 299634Viral capsid protein [50597] (3 species)
    1. 299635Species Semliki forest virus [TaxId:11033] [50599] (2 PDB entries)
    2. 299641Species Sindbis virus [TaxId:11034] [50598] (10 PDB entries)
    3. 299657Species Venezuelan equine encephalitis virus [TaxId:11036] [89347] (2 PDB entries)

More info for Family b.47.1.3: Viral proteases

Timeline for Family b.47.1.3: Viral proteases: