Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056594Protein Thrombin [50531] (2 species)
  7. 2056630Species Human (Homo sapiens) [TaxId:9606] [50532] (170 PDB entries)
    Uniprot P00734 331-361,364-421 ! Uniprot P00734 334-360 364-510 518-619 ! Uniprot P00734 328-620 ! Uniprot P00734 355-621 ! Uniprot P00734 328-620

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1a2c:
  2. Domain(s) for 1a3b:
  3. Domain(s) for 1a3e:
  4. Domain(s) for 1a46:
  5. Domain(s) for 1a4w:
  6. Domain(s) for 1a5g:
  7. Domain(s) for 1a61:
  8. Domain(s) for 1abi:
  9. Domain(s) for 1abj:
  10. Domain(s) for 1ad8:
  11. Domain(s) for 1ae8:
  12. Domain(s) for 1afe:
  13. Domain(s) for 1aht:
  14. Domain(s) for 1ai8:
  15. Domain(s) for 1aix:
  16. Domain(s) for 1awf:
  17. Domain(s) for 1awh:
    1. 2056811Domain d1awh.1: 1awh A:,B: [26191]
      complexed with gr3
    2. 2056812Domain d1awh.2: 1awh C:,D: [26192]
      complexed with gr3
  18. Domain(s) for 1ay6:
  19. Domain(s) for 1b5g:
  20. Domain(s) for 1b7x:
  21. Domain(s) for 1ba8:
  22. Domain(s) for 1bb0:
  23. Domain(s) for 1bcu:
  24. Domain(s) for 1bhx:
  25. Domain(s) for 1bmm:
  26. Domain(s) for 1bmn:
  27. Domain(s) for 1c1u:
  28. Domain(s) for 1c1v:
  29. Domain(s) for 1c1w:
  30. Domain(s) for 1c4u:
  31. Domain(s) for 1c4v:
  32. Domain(s) for 1c4y:
  33. Domain(s) for 1c5l:
  34. Domain(s) for 1c5n:
  35. Domain(s) for 1c5o:
  36. Domain(s) for 1ca8:
  37. Domain(s) for 1d3d:
  38. Domain(s) for 1d3p:
  39. Domain(s) for 1d3q:
  40. Domain(s) for 1d3t:
  41. Domain(s) for 1d4p:
  42. Domain(s) for 1d6w:
  43. Domain(s) for 1d9i:
  44. Domain(s) for 1de7:
    1. 2056680Domain d1de7.1: 1de7 L:,H: [26095]
      complexed with na
    2. 2056681Domain d1de7.2: 1de7 J:,K: [26096]
      complexed with na
  45. Domain(s) for 1dit:
  46. Domain(s) for 1dm4:
  47. Domain(s) for 1doj:
  48. Domain(s) for 1dwb:
  49. Domain(s) for 1dwc:
  50. Domain(s) for 1dwd:
  51. Domain(s) for 1dwe:
  52. Domain(s) for 1dx5:
    1. 2056751Domain d1dx5.1: 1dx5 A:,M: [26155]
      Other proteins in same PDB: d1dx5i1, d1dx5i2, d1dx5i3, d1dx5j1, d1dx5j2, d1dx5j3, d1dx5k1, d1dx5k2, d1dx5k3, d1dx5l1, d1dx5l2, d1dx5l3
      complexed with ca, fmt, na, ndg
    2. 2056752Domain d1dx5.2: 1dx5 B:,N: [26156]
      Other proteins in same PDB: d1dx5i1, d1dx5i2, d1dx5i3, d1dx5j1, d1dx5j2, d1dx5j3, d1dx5k1, d1dx5k2, d1dx5k3, d1dx5l1, d1dx5l2, d1dx5l3
      complexed with ca, fmt, na, ndg
    3. 2056753Domain d1dx5.3: 1dx5 C:,O: [26157]
      Other proteins in same PDB: d1dx5i1, d1dx5i2, d1dx5i3, d1dx5j1, d1dx5j2, d1dx5j3, d1dx5k1, d1dx5k2, d1dx5k3, d1dx5l1, d1dx5l2, d1dx5l3
      complexed with ca, fmt, na, ndg
    4. 2056754Domain d1dx5.4: 1dx5 D:,P: [26158]
      Other proteins in same PDB: d1dx5i1, d1dx5i2, d1dx5i3, d1dx5j1, d1dx5j2, d1dx5j3, d1dx5k1, d1dx5k2, d1dx5k3, d1dx5l1, d1dx5l2, d1dx5l3
      complexed with ca, fmt, na, ndg
  53. Domain(s) for 1e0f:
    1. 2056804Domain d1e0f.1: 1e0f A:,D: [26184]
      Other proteins in same PDB: d1e0fi_, d1e0fj_, d1e0fk_
    2. 2056805Domain d1e0f.2: 1e0f B:,E: [26185]
      Other proteins in same PDB: d1e0fi_, d1e0fj_, d1e0fk_
    3. 2056806Domain d1e0f.3: 1e0f C:,F: [26186]
      Other proteins in same PDB: d1e0fi_, d1e0fj_, d1e0fk_
  54. Domain(s) for 1eb1:
  55. Domain(s) for 1eoj:
  56. Domain(s) for 1eol:
  57. Domain(s) for 1fpc:
  58. Domain(s) for 1fph:
  59. Domain(s) for 1g30:
  60. Domain(s) for 1g32:
  61. Domain(s) for 1g37:
  62. Domain(s) for 1ghv:
  63. Domain(s) for 1ghw:
  64. Domain(s) for 1ghx:
  65. Domain(s) for 1ghy:
  66. Domain(s) for 1gj4:
  67. Domain(s) for 1gj5:
  68. Domain(s) for 1h8d:
  69. Domain(s) for 1h8i:
  70. Domain(s) for 1hag:
  71. Domain(s) for 1hah:
  72. Domain(s) for 1hai:
  73. Domain(s) for 1hao:
  74. Domain(s) for 1hap:
  75. Domain(s) for 1hbt:
  76. Domain(s) for 1hdt:
  77. Domain(s) for 1hgt:
  78. Domain(s) for 1hlt:
    1. 2056800Domain d1hlt.1: 1hlt L:,H: [26181]
      complexed with 0g6
    2. 2056801Domain d1hlt.2: 1hlt J:,K: [26182]
      complexed with 0g6
  79. Domain(s) for 1hut:
  80. Domain(s) for 1hxe:
  81. Domain(s) for 1hxf:
  82. Domain(s) for 1ihs:
  83. Domain(s) for 1iht:
  84. Domain(s) for 1jmo:
    • 2056825Domain d1jmo.1: 1jmo L:,H: [77137]
      Other proteins in same PDB: d1jmoa_
      complex with a heparin cofactor II mutant
      complexed with mpd, na, nag, ndg
  85. Domain(s) for 1jou:
    1. 2056667Domain d1jou.1: 1jou A:,B: [63218]
      complexed with acy, gol, na, ndg
    2. 2056668Domain d1jou.2: 1jou C:,D: [63219]
      complexed with acy, gol, na, ndg
    3. 2056669Domain d1jou.3: 1jou E:,F: [63220]
      complexed with acy, gol, na, ndg
  86. Domain(s) for 1jwt:
  87. Domain(s) for 1k21:
  88. Domain(s) for 1k22:
  89. Domain(s) for 1kts:
  90. Domain(s) for 1ktt:
  91. Domain(s) for 1lhc:
  92. Domain(s) for 1lhd:
  93. Domain(s) for 1lhe:
  94. Domain(s) for 1lhf:
  95. Domain(s) for 1lhg:
  96. Domain(s) for 1mh0:
    1. 2056795Domain d1mh0a_: 1mh0 A: [79110]
      anticoagulant slow form
      complexed with nag
    2. 2056796Domain d1mh0b_: 1mh0 B: [79111]
      anticoagulant slow form
      complexed with nag
  97. Domain(s) for 1mu6:
  98. Domain(s) for 1mu8:
  99. Domain(s) for 1mue:
  100. Domain(s) for 1nm6:
  101. Domain(s) for 1no9:
  102. Domain(s) for 1nrn:
  103. Domain(s) for 1nro:
  104. Domain(s) for 1nrp:
  105. Domain(s) for 1nrq:
  106. Domain(s) for 1nrr:
  107. Domain(s) for 1nrs:
  108. Domain(s) for 1nt1:
  109. Domain(s) for 1nu7:
    1. 2056742Domain d1nu7.1: 1nu7 A:,B: [92189]
      Other proteins in same PDB: d1nu7d1, d1nu7d2, d1nu7h1, d1nu7h2
      complexed with 0zj, hg, imd
    2. 2056743Domain d1nu7.2: 1nu7 E:,F: [92190]
      Other proteins in same PDB: d1nu7d1, d1nu7d2, d1nu7h1, d1nu7h2
      complexed with 0zj, hg, imd
  110. Domain(s) for 1nu9:
    1. 2056725Domain d1nu9a_: 1nu9 A: [92199]
      Other proteins in same PDB: d1nu9c1, d1nu9c2, d1nu9f1, d1nu9f2
      complexed with 0zj, hg, imd
    2. 2056726Domain d1nu9d_: 1nu9 D: [92202]
      Other proteins in same PDB: d1nu9c1, d1nu9c2, d1nu9f1, d1nu9f2
      complexed with 0zj, hg, imd
  111. Domain(s) for 1ny2:
  112. Domain(s) for 1nzq:
  113. Domain(s) for 1o0d:
  114. Domain(s) for 1o2g:
  115. Domain(s) for 1o5g:
  116. Domain(s) for 1ook:
  117. Domain(s) for 1oyt:
  118. Domain(s) for 1p8v:
  119. Domain(s) for 1ppb:
  120. Domain(s) for 1qbv:
  121. Domain(s) for 1qhr:
  122. Domain(s) for 1qj1:
  123. Domain(s) for 1qj6:
  124. Domain(s) for 1qj7:
  125. Domain(s) for 1qur:
  126. Domain(s) for 1rd3:
    1. 2056784Domain d1rd3.1: 1rd3 A:,B: [97302]
      complexed with gol, po4
    2. 2056785Domain d1rd3.2: 1rd3 C:,D: [97303]
      complexed with gol, po4
  127. Domain(s) for 1riw:
  128. Domain(s) for 1sb1:
  129. Domain(s) for 1sfq:
    1. 2056661Domain d1sfq.1: 1sfq A:,B: [105498]
      complexed with 0g6, na, nag; mutant
    2. 2056662Domain d1sfq.2: 1sfq D:,E: [105499]
      complexed with 0g6, na, nag; mutant
  130. Domain(s) for 1sg8:
    1. 2056765Domain d1sg8.1: 1sg8 A:,B: [105524]
      complexed with na, nag
    2. 2056766Domain d1sg8.2: 1sg8 D:,E: [105525]
      complexed with na, nag
  131. Domain(s) for 1sgi:
    1. 2056757Domain d1sgi.1: 1sgi A:,B: [105533]
      complexed with nag
    2. 2056758Domain d1sgi.2: 1sgi D:,E: [105534]
      complexed with nag
  132. Domain(s) for 1shh:
    1. 2056632Domain d1shh.1: 1shh A:,B: [105552]
      complexed with 0g6, nag
    2. 2056633Domain d1shh.2: 1shh D:,E: [105553]
      complexed with 0g6, nag
  133. Domain(s) for 1sl3:
  134. Domain(s) for 1sr5:
  135. Domain(s) for 1ta2:
  136. Domain(s) for 1ta6:
  137. Domain(s) for 1tb6:
  138. Domain(s) for 1tbz:
  139. Domain(s) for 1thp:
  140. Domain(s) for 1thr:
  141. Domain(s) for 1ths:
  142. Domain(s) for 1tmb:
  143. Domain(s) for 1tmt:
  144. Domain(s) for 1tmu:
  145. Domain(s) for 1tom:
  146. Domain(s) for 1tq0:
    1. 2056798Domain d1tq0.1: 1tq0 A:,B: [107196]
      mutant
    2. 2056799Domain d1tq0.2: 1tq0 C:,D: [107197]
      mutant
  147. Domain(s) for 1tq7:
  148. Domain(s) for 1uma:
  149. Domain(s) for 1uvs:
  150. Domain(s) for 1vr1:
  151. Domain(s) for 1xm1:
  152. Domain(s) for 1xmn:
    1. 2056657Domain d1xmn.1: 1xmn A:,B: [115495]
      complexed with 0g6, gol, na
    2. 2056658Domain d1xmn.2: 1xmn C:,D: [115496]
      complexed with 0g6, gol, na
    3. 2056659Domain d1xmn.3: 1xmn E:,F: [115497]
      complexed with 0g6, gol, na
    4. 2056660Domain d1xmn.4: 1xmn G:,H: [115498]
      complexed with 0g6, gol, na
  153. Domain(s) for 2a45:
    1. 2056822Domain d2a45.1: 2a45 A:,B: [162661]
      Other proteins in same PDB: d2a45g_, d2a45h_, d2a45i_, d2a45j_, d2a45k_, d2a45l_
      complexed with 0g6, po4
    2. 2056823Domain d2a45.2: 2a45 D:,E: [162662]
      Other proteins in same PDB: d2a45g_, d2a45h_, d2a45i_, d2a45j_, d2a45k_, d2a45l_
      complexed with 0g6, po4
  154. Domain(s) for 2hgt:
  155. Domain(s) for 2hnt:
  156. Domain(s) for 2hpp:
  157. Domain(s) for 2hpq:
  158. Domain(s) for 2thf:
  159. Domain(s) for 3hat:
  160. Domain(s) for 3htc:
  161. Domain(s) for 3k65:
  162. Domain(s) for 3sqe:
  163. Domain(s) for 4h6t:
  164. Domain(s) for 4hfy:
    1. 2056817Domain d4hfya_: 4hfy A: [307516]
      automated match to d4rn6a_
      mutant
    2. 2056818Domain d4hfyb_: 4hfy B: [307517]
      automated match to d4rn6a_
      mutant
  165. Domain(s) for 4htc:
  166. Domain(s) for 4rn6:
    1. 2056819Domain d4rn6a_: 4rn6 A: [260812]
      automated match to d3sqhe_
      complexed with 15u; mutant
    2. 2056820Domain d4rn6b_: 4rn6 B: [260811]
      automated match to d3sqhe_
      complexed with 15u; mutant
  167. Domain(s) for 4thn:
  168. Domain(s) for 5gds:
  169. Domain(s) for 7kme:
  170. Domain(s) for 8kme:

More info for Species Human (Homo sapiens) [TaxId:9606] from b.47.1.2 Thrombin

Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.47.1.2 Thrombin: