SCOP 1.69: Family b.43.3.1: Elongation factors

Lineage for Family b.43.3.1: Elongation factors

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.43: Reductase/isomerase/elongation factor common domain [50412] (4 superfamilies)
   barrel, closed; n=6, S=10; greek-key

4. Superfamily b.43.3: Translation proteins [50447] (2 families)

5. Family b.43.3.1: Elongation factors [50448] (8 proteins)

Proteins:

1. Elongation factor 2 (eEF-2), domain II [82118] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82119] (3 PDB entries)

2. Elongation factor eEF-1alpha, domain 2 [50454] (2 species)
   eukaryotic and archaeal homologue of EF-Tu

   1. Species Archaeon Sulfolobus solfataricus [TaxId:2287] [69276] (2 PDB entries)

   2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [50455] (4 PDB entries)

3. Elongation factor G (EF-G), domain II [50456] (1 species)

   • Species Thermus thermophilus [TaxId:274] [50457] (6 PDB entries)

4. Elongation factor Tu (EF-Tu), domain 2 [50449] (4 species)
   N-terminal domain is related to G proteins; C-terminal domain is (6,10) barrel of circularly permuted topology

   1. Species Cow (Bos taurus), mitochondrial [TaxId:9913] [50453] (1 PDB entry)

   2. Species Escherichia coli [TaxId:562] [50450] (5 PDB entries)

   3. Species Thermus aquaticus [TaxId:271] [50451] (4 PDB entries)

   4. Species Thermus thermophilus [TaxId:274] [50452] (3 PDB entries)

5. Eukaryotic peptide chain release factor ERF2, post-G domain [110225] (1 species)

   • Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [110226] (3 PDB entries)

6. Hypothetical protein PF0907 [110227] (1 species)
   stand-alone protein related to this domain

   • Species Pyrococcus furiosus [TaxId:186497] [110228] (1 PDB entry)

7. Initiation factor eIF2 gamma subunit, domain II [74962] (2 species)

   1. Species Archaeon Methanococcus jannaschii [TaxId:2190] [101788] (1 PDB entry)

   2. Species Archaeon Pyrococcus abyssi [TaxId:29292] [74963] (5 PDB entries)

8. Initiation factor IF2/eIF5b, domains 2 and 4 [50458] (2 species)
   the C-terminal domain 4 has the same fold as domain 2; it probably binds fMet-tRNAfmet

   1. Species Archaeon Methanobacterium thermoautotrophicum [TaxId:145262] [50459] (3 PDB entries)

   2. Species Bacillus stearothermophilus [TaxId:1422] [50460] (1 PDB entry)

More info for Family b.43.3.1: Elongation factors

Timeline for Family b.43.3.1: Elongation factors:

• Family b.43.3.1: Elongation factors first appeared (with stable ids) in SCOP 1.55
  
• Family b.43.3.1: Elongation factors appears in SCOP 1.67
  
• Family b.43.3.1: Elongation factors appears in SCOP 1.71
  
• Family b.43.3.1: Elongation factors appears in the current release, SCOPe 2.08