Lineage for Family b.43.3.1: Elongation factors

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2054165Fold b.43: Reductase/isomerase/elongation factor common domain [50412] (4 superfamilies)
    barrel, closed; n=6, S=10; greek-key
  4. 2054227Superfamily b.43.3: Translation proteins [50447] (7 families) (S)
  5. 2054228Family b.43.3.1: Elongation factors [50448] (10 protein domains)

Protein Domains:

  1. 2054229Elongation factor 2 (eEF-2), domain II [82118] (2 species)
    1. 2054230Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82119] (13 PDB entries)
      Uniprot P32324
    2. 2054256Species Human (Homo sapiens) [TaxId:9606] [268002] (1 PDB entry)
  2. 2054258Elongation factor eEF-1alpha, domain 2 [50454] (2 species)
    eukaryotic and archaeal homologue of EF-Tu
    1. 2054259Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [50455] (6 PDB entries)
    2. 2054266Species Sulfolobus solfataricus [TaxId:2287] [69276] (2 PDB entries)
      Uniprot P35021
  3. 2054271Elongation factor G (EF-G), domain II [50456] (2 species)
    1. 2054272Species Thermus thermophilus [TaxId:274] [50457] (9 PDB entries)
    2. 2054283Species Thermus thermophilus, EF-G-2 [TaxId:274] [141334] (2 PDB entries)
      Uniprot Q5SI76 268-370
      TTHA1498
  4. 2054286Elongation factor SelB, domains 2 and 4 [117218] (1 species)
    EF-Tu homologue, contains extra C-terminal domain (domain 4) of the same fold as the postG domain 2
  5. 2054312Elongation factor Tu (EF-Tu), domain 2 [50449] (4 species)
    N-terminal domain is related to G proteins; C-terminal domain is (6,10) barrel of circularly permuted topology
    1. 2054313Species Cow (Bos taurus), mitochondrial [TaxId:9913] [50453] (2 PDB entries)
      Uniprot P49410 56-452
    2. 2054319Species Escherichia coli [TaxId:562] [50450] (8 PDB entries)
      Uniprot P02990
    3. 2054334Species Thermus aquaticus [TaxId:271] [50451] (4 PDB entries)
    4. 2054343Species Thermus thermophilus [TaxId:274] [50452] (4 PDB entries)
  6. 2054352Eukaryotic peptide chain release factor ERF2, post-G domain [110225] (1 species)
  7. 2054357Hypothetical protein PF0907 [110227] (1 species)
    stand-alone protein related to this domain
  8. 2054361Initiation factor eIF2 gamma subunit, domain II [74962] (3 species)
    1. 2054362Species Methanococcus jannaschii [TaxId:2190] [101788] (1 PDB entry)
    2. 2054364Species Pyrococcus abyssi [TaxId:29292] [74963] (5 PDB entries)
    3. 2054370Species Sulfolobus solfataricus [TaxId:2287] [141335] (10 PDB entries)
      Uniprot Q980A5 207-320
  9. 2054388Initiation factor IF2/eIF5b, domains 2 and 4 [50458] (2 species)
    the C-terminal domain 4 has the same fold as domain 2; it probably binds fMet-tRNAfmet
    1. 2054389Species Bacillus stearothermophilus [TaxId:1422] [50460] (1 PDB entry)
    2. 2054391Species Methanobacterium thermoautotrophicum [TaxId:145262] [50459] (3 PDB entries)
  10. 2054398Sulfate adenylate transferase subunit cysN/C, EF-Tu domain 2-like domain [141336] (1 species)

More info for Family b.43.3.1: Elongation factors

Timeline for Family b.43.3.1: Elongation factors: