SCOPe 2.02: Family b.42.4.2: Clostridium neurotoxins, C-terminal domain

Lineage for Family b.42.4.2: Clostridium neurotoxins, C-terminal domain

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.4: STI-like [50386] (3 families)

5. Family b.42.4.2: Clostridium neurotoxins, C-terminal domain [50399] (2 proteins)
   overall fold is very similar to that of the STI family

Proteins:

1. Botulinum neurotoxin [50402] (2 species)

   1. Species Clostridium botulinum, serotype A [TaxId:1491] [50403] (1 PDB entry)

   2. Species Clostridium botulinum, serotype B [TaxId:1491] [50404] (16 PDB entries)

2. Tetanus neurotoxin [50400] (1 species)

   • Species Clostridium tetani [TaxId:1513] [50401] (10 PDB entries)

More info for Family b.42.4.2: Clostridium neurotoxins, C-terminal domain

Timeline for Family b.42.4.2: Clostridium neurotoxins, C-terminal domain:

• Family b.42.4.2: Clostridium neurotoxins, C-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family b.42.4.2: Clostridium neurotoxins, C-terminal domain appears in SCOPe 2.01
  
• Family b.42.4.2: Clostridium neurotoxins, C-terminal domain appears in SCOPe 2.03
  
• Family b.42.4.2: Clostridium neurotoxins, C-terminal domain appears in the current release, SCOPe 2.08