SCOP 1.75: Family b.42.2.1: Ricin B-like

Lineage for Family b.42.2.1: Ricin B-like

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.2: Ricin B-like lectins [50370] (3 families)

5. Family b.42.2.1: Ricin B-like [50371] (10 proteins)

Proteins:

1. 29-kDa galactose-binding lectin [159148] (1 species)
   duplication: tadem repeat of two Ricin B-like domains

   • Species Lumbricus terrestris [TaxId:6398] [159149] (2 PDB entries)
     Uniprot O96048 131-260

2. Agglutinin MOA, N-terminal domain [159152] (1 species)

   • Species Fairy-ring mushroom (Marasmius oreades) [TaxId:181124] [159153] (1 PDB entry)
     Uniprot Q8X123 2-155

3. Agglutinin-1 chain B [159150] (1 species)

   • Species Abrus precatorius [TaxId:3816] [159151] (1 PDB entry)
     Uniprot Q9M6E9 287-420! Uniprot Q9M6E9 421-547

4. Cytolethal distending toxin subunit A [110207] (2 species)

   1. Species Actinobacillus actinomycetemcomitans [TaxId:714] [141329] (1 PDB entry)
      Uniprot O87120 70-222

   2. Species Haemophilus ducreyi [TaxId:730] [110208] (1 PDB entry)
      Uniprot O06522 57-223

5. Cytolethal distending toxin subunit C [110209] (2 species)

   1. Species Actinobacillus actinomycetemcomitans [TaxId:714] [141330] (1 PDB entry)
      Uniprot Q7DK11 25-178

   2. Species Haemophilus ducreyi [TaxId:730] [110210] (1 PDB entry)
      Uniprot O06524 25-178

6. Hemagglutinin component Ha1 [101784] (2 species)

   1. Species Clostridium botulinum D phage [TaxId:29342] [101785] (1 PDB entry)

   2. Species Clostridium botulinum [TaxId:1491] [159147] (3 PDB entries)

7. Hemolytic lectin CEL-III, domains 1 and 2 [110211] (1 species)

   • Species Cucumaria echinata [TaxId:40245] [110212] (3 PDB entries)
     Uniprot Q868M7 11-442

8. Plant cytotoxin B-chain (lectin) [50372] (5 species)
   duplication: consists of two domains of this fold

   1. Species Abrus precatorius [TaxId:3816] [50374] (1 PDB entry)

   2. Species Castor bean (Ricinus communis), Ricin [TaxId:3988] [50373] (2 PDB entries)
      Uniprot P06750 303-564

   3. Species European mistletoe (Viscum album) [TaxId:3972] [50375] (14 PDB entries)
      different sequence variants
      Uniprot Q6ITZ3 266-520; Uniprot P81446 269-531 # 91% sequence identity

   4. Species Mongolian snake-gourd (Trichosanthes kirilowii), Lectin 1 [TaxId:3677] [89337] (1 PDB entry)

   5. Species Sambucus ebulus, ebulin [TaxId:28503] [50376] (4 PDB entries)

9. Polypeptide N-acetylgalactosaminyltransferase 1, C-terminal domain [117210] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [117211] (1 PDB entry)
     Uniprot O08912

10. Xylan binding domain, CBM13 (Endo-1,4-beta-xylanase C-terminal domain) [50377] (2 species)

    1. Species Streptomyces lividans [TaxId:1916] [74958] (3 PDB entries)

    2. Species Streptomyces olivaceoviridis [TaxId:1921] [50378] (11 PDB entries)

More info for Family b.42.2.1: Ricin B-like

Timeline for Family b.42.2.1: Ricin B-like:

• Family b.42.2.1: Ricin B-like first appeared (with stable ids) in SCOP 1.55
  
• Family b.42.2.1: Ricin B-like appears in SCOP 1.73
  
• Family b.42.2.1: Ricin B-like appears in SCOPe 2.01
  
• Family b.42.2.1: Ricin B-like appears in the current release, SCOPe 2.08