Lineage for Family b.42.1.2: Interleukin-1 (IL-1)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2384842Fold b.42: beta-Trefoil [50352] (8 superfamilies)
    barrel, closed; n=6, S=12; and a hairpin triplet; meander
    duplication: has internal pseudo threefold symmetry
  4. 2384843Superfamily b.42.1: Cytokine [50353] (3 families) (S)
  5. 2385158Family b.42.1.2: Interleukin-1 (IL-1) [50362] (6 protein domains)

Protein Domains:

  1. 2385159Interleukin-1 receptor antagonist protein [50366] (1 species)
  2. 2385169Interleukin-18 [101782] (1 species)
  3. 2385183Interleukin-1alpha [50368] (1 species)
  4. 2385186Interleukin-1beta [50363] (2 species)
    1. 2385187Species Human (Homo sapiens) [TaxId:9606] [50364] (26 PDB entries)
      Uniprot P01584 117-269
    2. 2385215Species Mouse (Mus musculus) [TaxId:10090] [50365] (2 PDB entries)
  5. 2385218Interleukin-1F5 [101780] (1 species)
  6. 2385221automated matches [190999] (1 species)
    not a true protein

More info for Family b.42.1.2: Interleukin-1 (IL-1)

Timeline for Family b.42.1.2: Interleukin-1 (IL-1):