Class b: All beta proteins [48724] (176 folds) |
Fold b.42: beta-Trefoil [50352] (8 superfamilies) barrel, closed; n=6, S=12; and a hairpin triplet; meander duplication: has internal pseudo threefold symmetry |
Superfamily b.42.1: Cytokine [50353] (3 families) |
Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (10 proteins) |
Protein Acidic FGF (FGF1) [50357] (4 species) |
Species Human (Homo sapiens) [TaxId:9606] [50359] (92 PDB entries) Uniprot P05230 16-152 ! Uniprot P05230 |
Domain d1axma_: 1axm A: [25521] heparin-linked biologically-active dimer |
Domain d1axmb_: 1axm B: [25522] heparin-linked biologically-active dimer |
Domain d1axmc_: 1axm C: [25523] heparin-linked biologically-active dimer |
Domain d1axmd_: 1axm D: [25524] heparin-linked biologically-active dimer |
Domain d1axme_: 1axm E: [25525] heparin-linked biologically-active dimer |
Domain d1axmf_: 1axm F: [25526] heparin-linked biologically-active dimer |
Domain d1djsb_: 1djs B: [25518] Other proteins in same PDB: d1djsa1, d1djsa2 complexed with so4 |
Domain d1dzca_: 1dzc A: [25531] mutant |
Domain d1dzda_: 1dzd A: [25532] |
Domain d1e0oa_: 1e0o A: [25529] Other proteins in same PDB: d1e0ob1, d1e0ob2, d1e0od1, d1e0od2 complexed with ni, so4 |
Domain d1e0oc_: 1e0o C: [25530] Other proteins in same PDB: d1e0ob1, d1e0ob2, d1e0od1, d1e0od2 complexed with ni, so4 |
Domain d1evta_: 1evt A: [25527] Other proteins in same PDB: d1evtc1, d1evtc2, d1evtd1, d1evtd2 complexed with so4 |
Domain d1evtb_: 1evt B: [25528] Other proteins in same PDB: d1evtc1, d1evtc2, d1evtd1, d1evtd2 complexed with so4 |
Domain d1hkna_: 1hkn A: [90638] complexed with n2m |
Domain d1hknb_: 1hkn B: [90639] complexed with n2m |
Domain d1hknc_: 1hkn C: [90640] complexed with n2m |
Domain d1hknd_: 1hkn D: [90641] complexed with n2m |
Domain d1hkne_: 1hkn E: [90642] complexed with n2m |
Domain d1hknf_: 1hkn F: [90643] complexed with n2m |
Domain d1jqza_: 1jqz A: [67109] complexed with fmt |
Domain d1jqzb_: 1jqz B: [67110] complexed with fmt |
Domain d1jt3a_: 1jt3 A: [67241] complexed with so4 |
Domain d1jt3b_: 1jt3 B: [67242] complexed with so4 |
Domain d1jt4a_: 1jt4 A: [67243] complexed with fmt |
Domain d1jt4b_: 1jt4 B: [67244] complexed with fmt |
Domain d1jt5a_: 1jt5 A: [67245] complexed with so4 |
Domain d1jt5b_: 1jt5 B: [67246] complexed with so4 |
Domain d1jt7a_: 1jt7 A: [67255] complexed with fmt, so4 |
Domain d1jt7b_: 1jt7 B: [67256] complexed with fmt, so4 |
Domain d1jt7c_: 1jt7 C: [67257] complexed with fmt, so4 |
Domain d1jt7d_: 1jt7 D: [67258] complexed with fmt, so4 |
Domain d1jtca_: 1jtc A: [67260] complexed with fmt |
Domain d1jtcb_: 1jtc B: [67261] complexed with fmt |
Domain d1jtcc_: 1jtc C: [67262] complexed with fmt |
Domain d1jtcd_: 1jtc D: [67263] complexed with fmt |
Domain d1jy0a_: 1jy0 A: [90923] complexed with fmt |
Domain d1jy0b_: 1jy0 B: [90924] complexed with fmt |
Domain d1k5ua_: 1k5u A: [68207] complexed with so4 |
Domain d1k5ub_: 1k5u B: [68208] complexed with so4 |
Domain d1k5uc_: 1k5u C: [68209] complexed with so4 |
Domain d1k5va_: 1k5v A: [68210] complexed with so4 |
Domain d1k5vb_: 1k5v B: [68211] complexed with so4 |
Domain d1m16a_: 1m16 A: [91164] complexed with fmt, so4 |
Domain d1m16b_: 1m16 B: [91165] complexed with fmt, so4 |
Domain d1nzka_: 1nzk A: [92378] complexed with fmt, so4; mutant |
Domain d1nzkb_: 1nzk B: [92379] complexed with fmt, so4; mutant |
Domain d1nzkc_: 1nzk C: [92380] complexed with fmt, so4; mutant |
Domain d1nzkd_: 1nzk D: [92381] complexed with fmt, so4; mutant |
Domain d1p63a_: 1p63 A: [94153] complexed with fmt, so4 |
Domain d1p63b_: 1p63 B: [94154] complexed with fmt, so4 |
Domain d1pzza_: 1pzz A: [104398] complexed with fmt, so4; mutant |
Domain d1pzzb_: 1pzz B: [104399] complexed with fmt, so4; mutant |
Domain d1q03a_: 1q03 A: [104400] mutant |
Domain d1q03b_: 1q03 B: [104401] mutant |
Domain d1q04a_: 1q04 A: [104402] complexed with fmt |
Domain d1q04b_: 1q04 B: [104403] complexed with fmt |
Domain d1rg8a_: 1rg8 A: [111801] complexed with fmt |
Domain d1rg8b_: 1rg8 B: [111802] complexed with fmt |
Domain d1rmla_: 1rml A: [25533] complexed with nts |
Domain d1ry7a_: 1ry7 A: [98091] Other proteins in same PDB: d1ry7b1, d1ry7b2 |
Domain d1ytoa_: 1yto A: [203229] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d1ytob_: 1yto B: [203230] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d1ytoc_: 1yto C: [203231] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d1ytod_: 1yto D: [203232] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d1z2va_: 1z2v A: [203295] automated match to d1q03a_ complexed with so4; mutant |
Domain d1z2vb_: 1z2v B: [203296] automated match to d1q03a_ complexed with so4; mutant |
Domain d1z4sa_: 1z4s A: [203297] automated match to d1q03a_ complexed with so4; mutant |
Domain d1z4sb_: 1z4s B: [203298] automated match to d1q03a_ complexed with so4; mutant |
Domain d1z4sc_: 1z4s C: [203299] automated match to d1q03a_ complexed with so4; mutant |
Domain d1z4sd_: 1z4s D: [203300] automated match to d1q03a_ complexed with so4; mutant |
Domain d2afga_: 2afg A: [25514] complexed with so4 |
Domain d2afgb_: 2afg B: [25515] complexed with so4 |
Domain d2afgc_: 2afg C: [25516] complexed with so4 |
Domain d2afgd_: 2afg D: [25517] complexed with so4 |
Domain d2aqza_: 2aqz A: [203478] automated match to d1q03a_ complexed with so4; mutant |
Domain d2aqzb_: 2aqz B: [203479] automated match to d1q03a_ complexed with so4; mutant |
Domain d2axma_: 2axm A: [25519] Heparin-linked biologically-active dimer |
Domain d2axmb_: 2axm B: [25520] Heparin-linked biologically-active dimer |
Domain d2erma_: 2erm A: [241789] automated match to d3ojma_ complexed with ipa |
Domain d2hw9a_: 2hw9 A: [204645] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d2hw9b_: 2hw9 B: [204646] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d2hwaa_: 2hwa A: [204647] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d2hwab_: 2hwa B: [204648] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d2hwma_: 2hwm A: [204649] automated match to d1q03a_ complexed with fmt; mutant |
Domain d2hwmb_: 2hwm B: [204650] automated match to d1q03a_ complexed with fmt; mutant |
Domain d2hz9a_: 2hz9 A: [204671] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d2hz9b_: 2hz9 B: [204672] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d2k43a_: 2k43 A: [242369] automated match to d1djsb_ |
Domain d2k4ab_: 2k4a B: [242372] Other proteins in same PDB: d2k4aa_ automated match to d1djsb_ |
Domain d2k8ra_: 2k8r A: [242419] automated match to d1djsb_ complexed with ihp |
Domain d2ki4a_: 2ki4 A: [242520] Other proteins in same PDB: d2ki4b_, d2ki4c_ automated match to d1djsb_ |
Domain d2ki4d_: 2ki4 D: [242523] Other proteins in same PDB: d2ki4b_, d2ki4c_ automated match to d1djsb_ |
Domain d2ntda_: 2ntd A: [205158] automated match to d1q03a_ complexed with fmt; mutant |
Domain d2ntdb_: 2ntd B: [205159] automated match to d1q03a_ complexed with fmt; mutant |
Domain d2ntdc_: 2ntd C: [205160] automated match to d1q03a_ complexed with fmt; mutant |
Domain d2ntdd_: 2ntd D: [205161] automated match to d1q03a_ complexed with fmt; mutant |
Domain d2q9xa_: 2q9x A: [205769] automated match to d1q03a_ complexed with gol; mutant |
Domain d3b9ua_: 3b9u A: [208576] automated match to d1q03a_ complexed with so4; mutant |
Domain d3ba4a_: 3ba4 A: [208577] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3ba4b_: 3ba4 B: [208578] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3ba5a_: 3ba5 A: [208579] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3ba5b_: 3ba5 B: [208580] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3ba7a_: 3ba7 A: [208585] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3ba7b_: 3ba7 B: [208586] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3bada_: 3bad A: [208587] automated match to d1q03a_ complexed with so4; mutant |
Domain d3badb_: 3bad B: [208588] automated match to d1q03a_ complexed with so4; mutant |
Domain d3baga_: 3bag A: [208589] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3bagb_: 3bag B: [208590] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3baha_: 3bah A: [208591] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3bahb_: 3bah B: [208592] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3baoa_: 3bao A: [208593] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3baob_: 3bao B: [208594] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3baqa_: 3baq A: [208595] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3baqb_: 3baq B: [208596] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3baua_: 3bau A: [208597] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3baub_: 3bau B: [208598] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3bava_: 3bav A: [208599] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3bavb_: 3bav B: [208600] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3bb2a_: 3bb2 A: [208601] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3bb2b_: 3bb2 B: [208602] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3cqaa_: 3cqa A: [173407] automated match to d1jqza_ complexed with fmt, so4; mutant |
Domain d3cqab_: 3cqa B: [173408] automated match to d1jqza_ complexed with fmt, so4; mutant |
Domain d3crga_: 3crg A: [208929] automated match to d1q03a_ complexed with fmt, gol, so4; mutant |
Domain d3crgb_: 3crg B: [208930] automated match to d1q03a_ complexed with fmt, gol, so4; mutant |
Domain d3crha_: 3crh A: [208931] automated match to d1q03a_ complexed with so4; mutant |
Domain d3crhb_: 3crh B: [208932] automated match to d1q03a_ complexed with so4; mutant |
Domain d3cria_: 3cri A: [208933] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3crib_: 3cri B: [208934] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3cu1b_: 3cu1 B: [208948] Other proteins in same PDB: d3cu1a_, d3cu1c_ automated match to d3oj2b_ complexed with scr |
Domain d3cu1d_: 3cu1 D: [208950] Other proteins in same PDB: d3cu1a_, d3cu1c_ automated match to d3oj2b_ complexed with scr |
Domain d3fgma_: 3fgm A: [209900] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fgmb_: 3fgm B: [209901] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fj8a_: 3fj8 A: [209953] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fj8b_: 3fj8 B: [209954] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fj9a_: 3fj9 A: [209955] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3fj9b_: 3fj9 B: [209956] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3fjaa_: 3fja A: [209957] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3fjab_: 3fja B: [209958] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3fjba_: 3fjb A: [209959] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fjbb_: 3fjb B: [209960] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fjca_: 3fjc A: [209961] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjcb_: 3fjc B: [209962] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjda_: 3fjd A: [209963] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjdb_: 3fjd B: [209964] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjea_: 3fje A: [209965] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjeb_: 3fje B: [209966] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjfa_: 3fjf A: [209967] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3fjfb_: 3fjf B: [209968] automated match to d1q03a_ complexed with fmt; mutant |
Domain d3fjha_: 3fjh A: [209969] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjhb_: 3fjh B: [209970] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjia_: 3fji A: [209971] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fjib_: 3fji B: [209972] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fjic_: 3fji C: [209973] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fjid_: 3fji D: [209974] automated match to d1q03a_ complexed with so4; mutant |
Domain d3fjja_: 3fjj A: [209975] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjjb_: 3fjj B: [209976] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjka_: 3fjk A: [209977] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjkb_: 3fjk B: [209978] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjkc_: 3fjk C: [209979] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3fjkd_: 3fjk D: [209980] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3homa_: 3hom A: [211172] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3homb_: 3hom B: [211173] automated match to d1q03a_ complexed with fmt, so4; mutant |
Domain d3juta_: 3jut A: [178837] automated match to d1hkne_ complexed with gtq |
Domain d3jutb_: 3jut B: [178838] automated match to d1hkne_ complexed with gtq |
Domain d3jutc_: 3jut C: [178839] automated match to d1hkne_ complexed with gtq |
Domain d3jutd_: 3jut D: [178840] automated match to d1hkne_ complexed with gtq |
Domain d3jute_: 3jut E: [178841] automated match to d1hkne_ complexed with gtq |
Domain d3jutf_: 3jut F: [178842] automated match to d1hkne_ complexed with gtq |
Domain d3k1xa_: 3k1x A: [178966] automated match to d1hkne_ complexed with dbx |
Domain d3k1xb_: 3k1x B: [178967] automated match to d1hkne_ complexed with dbx |
Domain d3k1xc_: 3k1x C: [178968] automated match to d1hkne_ complexed with dbx |
Domain d3k1xd_: 3k1x D: [178969] automated match to d1hkne_ complexed with dbx |
Domain d3k1xe_: 3k1x E: [178970] automated match to d1hkne_ complexed with dbx |
Domain d3k1xf_: 3k1x F: [178971] automated match to d1hkne_ complexed with dbx |
Domain d3o3qa_: 3o3q A: [182778] automated match to d1nzka_ complexed with gol; mutant |
Domain d3o3qb_: 3o3q B: [182779] automated match to d1nzka_ complexed with gol; mutant |
Domain d3o3qc_: 3o3q C: [182780] automated match to d1nzka_ complexed with gol; mutant |
Domain d3o3qd_: 3o3q D: [182781] automated match to d1nzka_ complexed with gol; mutant |
Domain d3ojma_: 3ojm A: [214378] Other proteins in same PDB: d3ojmb1, d3ojmb2 automated match to d1ry7a_ complexed with so4; mutant |
Domain d3ud7a_: 3ud7 A: [217302] automated match to d1q03a_ complexed with po4 |
Domain d3ud7b_: 3ud7 B: [217303] automated match to d1q03a_ complexed with po4 |
Domain d3ud7c_: 3ud7 C: [217304] automated match to d1q03a_ complexed with po4 |
Domain d3ud8a_: 3ud8 A: [217305] automated match to d1q03a_ complexed with po4 |
Domain d3ud8b_: 3ud8 B: [217306] automated match to d1q03a_ complexed with po4 |
Domain d3ud8c_: 3ud8 C: [217307] automated match to d1q03a_ complexed with po4 |
Domain d3ud9a_: 3ud9 A: [217308] automated match to d1q03a_ complexed with po4 |
Domain d3ud9b_: 3ud9 B: [217309] automated match to d1q03a_ complexed with po4 |
Domain d3ud9c_: 3ud9 C: [217310] automated match to d1q03a_ complexed with po4 |
Domain d3udaa_: 3uda A: [217311] automated match to d1q03a_ complexed with idy, po4, sus |
Domain d3udab_: 3uda B: [217312] automated match to d1q03a_ complexed with idy, po4, sus |
Domain d3udac_: 3uda C: [217313] automated match to d1q03a_ complexed with idy, po4, sus |
Domain d4q91a_: 4q91 A: [269780] automated match to d3ojma_ complexed with fmt, po4; mutant |
Domain d4q91b_: 4q91 B: [269784] automated match to d3ojma_ complexed with fmt, po4; mutant |
Domain d4q9ga_: 4q9g A: [269789] automated match to d3ojma_ complexed with fmt, po4; mutant |
Domain d4q9gb_: 4q9g B: [269788] automated match to d3ojma_ complexed with fmt, po4; mutant |
Domain d4q9pa_: 4q9p A: [269773] automated match to d3ojma_ mutant |
Domain d4q9pb_: 4q9p B: [269783] automated match to d3ojma_ mutant |
Domain d4qala_: 4qal A: [269794] automated match to d3ojma_ complexed with flc; mutant |
Domain d4qalb_: 4qal B: [269795] automated match to d3ojma_ complexed with flc; mutant |
Domain d4qbca_: 4qbc A: [269799] automated match to d3ojma_ complexed with fmt, so4; mutant |
Domain d4qbcb_: 4qbc B: [269798] automated match to d3ojma_ complexed with fmt, so4; mutant |
Domain d4qbva_: 4qbv A: [269797] automated match to d3ojma_ complexed with flc; mutant |
Domain d4qbvb_: 4qbv B: [269796] automated match to d3ojma_ complexed with flc; mutant |
Domain d4qc4a_: 4qc4 A: [269802] automated match to d3ojma_ complexed with flc, imd, na; mutant |
Domain d4qc4b_: 4qc4 B: [269803] automated match to d3ojma_ complexed with flc, imd, na; mutant |
Domain d4qo3a_: 4qo3 A: [272378] automated match to d3ojma_ complexed with flc, imd; mutant |
Domain d4qo3b_: 4qo3 B: [272377] automated match to d3ojma_ complexed with flc, imd; mutant |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.42.1.1 Acidic FGF (FGF1):