Lineage for Protein: Acidic FGF (FGF1)

  1. Root: SCOP 1.67
  2. 362614Class b: All beta proteins [48724] (141 folds)
  3. 375317Fold b.42: beta-Trefoil [50352] (6 superfamilies)
    barrel, closed; n=6, S=12; and a hairpin triplet; meander
    duplication: has internal pseudo threefold symmetry
  4. 375318Superfamily b.42.1: Cytokine [50353] (2 families) (S)
  5. 375319Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (8 proteins)
  6. 375320Protein Acidic FGF (FGF1) [50357] (3 species)

Species:

  1. 375321Cow (Bos taurus) [TaxId:9913] [50358] (2 PDB entries)
    1. Domains for 1afc:
      1. 375324Domain d1afca_: 1afc A: [25506]
      2. 375325Domain d1afcb_: 1afc B: [25507]
      3. 375326Domain d1afcc_: 1afc C: [25508]
      4. 375327Domain d1afcd_: 1afc D: [25509]
      5. 375328Domain d1afce_: 1afc E: [25510]
      6. 375329Domain d1afcf_: 1afc F: [25511]
      7. 375330Domain d1afcg_: 1afc G: [25512]
      8. 375331Domain d1afch_: 1afc H: [25513]
        complexed with scr; mutant
    2. Domains for 1bar:
      1. 375322Domain d1bara_: 1bar A: [25504]
      2. 375323Domain d1barb_: 1bar B: [25505]
        mutant
  2. 375332Eastern newt (Notophthalmus viridescens) [TaxId:8316] [63778] (1 PDB entry)
  3. 375334Human (Homo sapiens) [TaxId:9606] [50359] (23 PDB entries)
    1. Domains for 1axm:
      1. 375379Domain d1axma_: 1axm A: [25521]
      2. 375380Domain d1axmb_: 1axm B: [25522]
      3. 375381Domain d1axmc_: 1axm C: [25523]
      4. 375382Domain d1axmd_: 1axm D: [25524]
      5. 375383Domain d1axme_: 1axm E: [25525]
      6. 375384Domain d1axmf_: 1axm F: [25526]
        heparin-linked biologically-active dimer
        complexed with ids, sgn
    2. Domain for 1djs:
    3. Domain for 1dzc:
    4. Domain for 1dzd:
    5. Domains for 1e0o:
      1. 375387Domain d1e0oa_: 1e0o A: [25529]
        Other proteins in same PDB: d1e0ob1, d1e0ob2, d1e0od1, d1e0od2
      2. 375388Domain d1e0oc_: 1e0o C: [25530]
        Other proteins in same PDB: d1e0ob1, d1e0ob2, d1e0od1, d1e0od2
        complexed with 2si, ni, sgn, so4
    6. Domains for 1evt:
      1. 375385Domain d1evta_: 1evt A: [25527]
        Other proteins in same PDB: d1evtc1, d1evtc2, d1evtd1, d1evtd2
      2. 375386Domain d1evtb_: 1evt B: [25528]
        Other proteins in same PDB: d1evtc1, d1evtc2, d1evtd1, d1evtd2
        complexed with so4
    7. Domains for 1hkn:
      1. 375361Domain d1hkna_: 1hkn A: [90638]
      2. 375362Domain d1hknb_: 1hkn B: [90639]
      3. 375363Domain d1hknc_: 1hkn C: [90640]
      4. 375364Domain d1hknd_: 1hkn D: [90641]
      5. 375365Domain d1hkne_: 1hkn E: [90642]
      6. 375366Domain d1hknf_: 1hkn F: [90643]
        complexed with n2m
    8. Domains for 1jqz:
      1. 375335Domain d1jqza_: 1jqz A: [67109]
      2. 375336Domain d1jqzb_: 1jqz B: [67110]
        complexed with fmt
    9. Domains for 1jt3:
      1. 375355Domain d1jt3a_: 1jt3 A: [67241]
      2. 375356Domain d1jt3b_: 1jt3 B: [67242]
        complexed with so4; mutant
    10. Domains for 1jt4:
      1. 375347Domain d1jt4a_: 1jt4 A: [67243]
      2. 375348Domain d1jt4b_: 1jt4 B: [67244]
        complexed with fmt; mutant
    11. Domains for 1jt5:
      1. 375351Domain d1jt5a_: 1jt5 A: [67245]
      2. 375352Domain d1jt5b_: 1jt5 B: [67246]
        complexed with so4; mutant
    12. Domains for 1jt7:
      1. 375343Domain d1jt7a_: 1jt7 A: [67255]
      2. 375344Domain d1jt7b_: 1jt7 B: [67256]
      3. 375345Domain d1jt7c_: 1jt7 C: [67257]
      4. 375346Domain d1jt7d_: 1jt7 D: [67258]
        complexed with fmt, so4; mutant
    13. Domains for 1jtc:
      1. 375337Domain d1jtca_: 1jtc A: [67260]
      2. 375338Domain d1jtcb_: 1jtc B: [67261]
      3. 375339Domain d1jtcc_: 1jtc C: [67262]
      4. 375340Domain d1jtcd_: 1jtc D: [67263]
        complexed with fmt; mutant
    14. Domains for 1jy0:
      1. 375349Domain d1jy0a_: 1jy0 A: [90923]
      2. 375350Domain d1jy0b_: 1jy0 B: [90924]
        complexed with fmt; mutant
    15. Domains for 1k5u:
      1. 375371Domain d1k5ua_: 1k5u A: [68207]
      2. 375372Domain d1k5ub_: 1k5u B: [68208]
      3. 375373Domain d1k5uc_: 1k5u C: [68209]
        complexed with so4; mutant
    16. Domains for 1k5v:
      1. 375374Domain d1k5va_: 1k5v A: [68210]
      2. 375375Domain d1k5vb_: 1k5v B: [68211]
        complexed with so4; mutant
    17. Domains for 1m16:
      1. 375353Domain d1m16a_: 1m16 A: [91164]
      2. 375354Domain d1m16b_: 1m16 B: [91165]
        complexed with fmt, so4; mutant
    18. Domains for 1nzk:
      1. 375367Domain d1nzka_: 1nzk A: [92378]
      2. 375368Domain d1nzkb_: 1nzk B: [92379]
      3. 375369Domain d1nzkc_: 1nzk C: [92380]
      4. 375370Domain d1nzkd_: 1nzk D: [92381]
        complexed with fmt, so4; mutant
    19. Domains for 1p63:
      1. 375341Domain d1p63a_: 1p63 A: [94153]
      2. 375342Domain d1p63b_: 1p63 B: [94154]
        complexed with fmt, so4; mutant
    20. Domain for 1rml:
    21. Domain for 1ry7:
    22. Domains for 2afg:
      1. 375357Domain d2afga_: 2afg A: [25514]
      2. 375358Domain d2afgb_: 2afg B: [25515]
      3. 375359Domain d2afgc_: 2afg C: [25516]
      4. 375360Domain d2afgd_: 2afg D: [25517]
        complexed with so4
    23. Domains for 2axm:
      1. 375377Domain d2axma_: 2axm A: [25519]
      2. 375378Domain d2axmb_: 2axm B: [25520]
        Heparin-linked biologically-active dimer
        complexed with ids, sgn

More info for Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF)

Timeline for Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF):