SCOP 1.65: Protein: Acidic FGF (FGF1)

Lineage for Protein: Acidic FGF (FGF1)

Root: SCOP 1.65
Class b: All beta proteins [48724] (126 folds)
Fold b.42: beta-Trefoil [50352] (6 superfamilies)
barrel, closed; n=6, S=12; and a hairpin triplet; meander
duplication: has internal pseudo threefold symmetry
Superfamily b.42.1: Cytokine [50353] (2 families)
Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (6 proteins)
Protein Acidic FGF (FGF1) [50357] (3 species)

Species:

Cow (Bos taurus) [TaxId:9913] [50358] (2 PDB entries)
1. Domains for 1afc:
  1. Domain d1afca_: 1afc A: [25506]
  2. Domain d1afcb_: 1afc B: [25507]
  3. Domain d1afcc_: 1afc C: [25508]
  4. Domain d1afcd_: 1afc D: [25509]
  5. Domain d1afce_: 1afc E: [25510]
  6. Domain d1afcf_: 1afc F: [25511]
  7. Domain d1afcg_: 1afc G: [25512]
  8. Domain d1afch_: 1afc H: [25513]
    complexed with scr; mutant
2. Domains for 1bar:
  1. Domain d1bara_: 1bar A: [25504]
  2. Domain d1barb_: 1bar B: [25505]
    mutant
Eastern newt (Notophthalmus viridescens) [TaxId:8316] [63778] (1 PDB entry)
- Domain for 1fmm:
  - Domain d1fmms_: 1fmm S: [59883]
Human (Homo sapiens) [TaxId:9606] [50359] (17 PDB entries)
1. Domains for 1axm:
  1. Domain d1axma_: 1axm A: [25521]
  2. Domain d1axmb_: 1axm B: [25522]
  3. Domain d1axmc_: 1axm C: [25523]
  4. Domain d1axmd_: 1axm D: [25524]
  5. Domain d1axme_: 1axm E: [25525]
  6. Domain d1axmf_: 1axm F: [25526]
    heparin-linked biologically-active dimer
    complexed with ids, sgn
2. Domain for 1djs:
  - Domain d1djsb_: 1djs B: [25518]
    Other proteins in same PDB: d1djsa1, d1djsa2
3. Domain for 1dzc:
  - Domain d1dzca_: 1dzc A: [25531]
    mutant
4. Domain for 1dzd:
  - Domain d1dzda_: 1dzd A: [25532]
5. Domains for 1e0o:
  1. Domain d1e0oa_: 1e0o A: [25529]
    Other proteins in same PDB: d1e0ob1, d1e0ob2, d1e0od1, d1e0od2
  2. Domain d1e0oc_: 1e0o C: [25530]
    Other proteins in same PDB: d1e0ob1, d1e0ob2, d1e0od1, d1e0od2
    complexed with 2si, ni, sgn, so4
6. Domains for 1evt:
  1. Domain d1evta_: 1evt A: [25527]
    Other proteins in same PDB: d1evtc1, d1evtc2, d1evtd1, d1evtd2
  2. Domain d1evtb_: 1evt B: [25528]
    Other proteins in same PDB: d1evtc1, d1evtc2, d1evtd1, d1evtd2
    complexed with so4
7. Domains for 1jqz:
  1. Domain d1jqza_: 1jqz A: [67109]
  2. Domain d1jqzb_: 1jqz B: [67110]
    complexed with fmt
8. Domains for 1jt3:
  1. Domain d1jt3a_: 1jt3 A: [67241]
  2. Domain d1jt3b_: 1jt3 B: [67242]
    complexed with so4; mutant
9. Domains for 1jt4:
  1. Domain d1jt4a_: 1jt4 A: [67243]
  2. Domain d1jt4b_: 1jt4 B: [67244]
    complexed with fmt; mutant
10. Domains for 1jt5:
  1. Domain d1jt5a_: 1jt5 A: [67245]
  2. Domain d1jt5b_: 1jt5 B: [67246]
    complexed with so4; mutant
11. Domains for 1jt7:
  1. Domain d1jt7a_: 1jt7 A: [67255]
  2. Domain d1jt7b_: 1jt7 B: [67256]
  3. Domain d1jt7c_: 1jt7 C: [67257]
  4. Domain d1jt7d_: 1jt7 D: [67258]
    complexed with fmt, so4; mutant
12. Domains for 1jtc:
  1. Domain d1jtca_: 1jtc A: [67260]
  2. Domain d1jtcb_: 1jtc B: [67261]
  3. Domain d1jtcc_: 1jtc C: [67262]
  4. Domain d1jtcd_: 1jtc D: [67263]
    complexed with fmt; mutant
13. Domains for 1k5u:
  1. Domain d1k5ua_: 1k5u A: [68207]
  2. Domain d1k5ub_: 1k5u B: [68208]
  3. Domain d1k5uc_: 1k5u C: [68209]
    complexed with so4; mutant
14. Domains for 1k5v:
  1. Domain d1k5va_: 1k5v A: [68210]
  2. Domain d1k5vb_: 1k5v B: [68211]
    complexed with so4; mutant
15. Domain for 1rml:
  - Domain d1rml__: 1rml - [25533]
    complexed with nts
16. Domains for 2afg:
  1. Domain d2afga_: 2afg A: [25514]
  2. Domain d2afgb_: 2afg B: [25515]
  3. Domain d2afgc_: 2afg C: [25516]
  4. Domain d2afgd_: 2afg D: [25517]
    complexed with so4
17. Domains for 2axm:
  1. Domain d2axma_: 2axm A: [25519]
  2. Domain d2axmb_: 2axm B: [25520]
    Heparin-linked biologically-active dimer
    complexed with ids, sgn

More info for Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF)

Timeline for Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF):

Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF) first appeared (with stable ids) in SCOP 1.55
Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF) appears in SCOP 1.63
Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF) appears in SCOP 1.67
Protein Acidic FGF (FGF1) from b.42.1.1: Fibroblast growth factors (FGF) appears in the current release, SCOPe 2.08