SCOPe 2.01: Family b.42.1.1: Fibroblast growth factors (FGF)

Lineage for Family b.42.1.1: Fibroblast growth factors (FGF)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (10 proteins)

Proteins:

1. Acidic FGF (FGF1) [50357] (4 species)

   1. Species Cow (Bos taurus) [TaxId:9913] [50358] (2 PDB entries)

   2. Species Eastern newt (Notophthalmus viridescens) [TaxId:8316] [63778] (1 PDB entry)

   3. Species Human (Homo sapiens) [TaxId:9606] [50359] (31 PDB entries)
      Uniprot P05230 16-152 ! Uniprot P05230

   4. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [189149] (1 PDB entry)

2. Basic FGF (FGF2) [50355] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50356] (16 PDB entries)

3. Fibrobast growth factor homologous factor 1 (FHF1b, FGF12b) [101776] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101777] (1 PDB entry)

4. Fibroblast growth factor 4 (FGF4) [63779] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [63780] (1 PDB entry)

5. Fibroblast growth factor 8, FGF8 [159145] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159146] (1 PDB entry)
     Uniprot P55075 52-198

6. Fibroblast growth factor 9, FGF9 [63781] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [63782] (2 PDB entries)

7. Fibroblast growth factor-10, FGF10 [82107] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [82108] (1 PDB entry)

8. Fibroblast growth factor-19 (FGF19) [101778] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101779] (2 PDB entries)

9. Keratinocyte growth factor, FGF7 [50360] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [50361] (2 PDB entries)

10. automated matches [190637] (2 species)
    not a true protein

    1. Species Human (Homo sapiens) [TaxId:9606] [187699] (1 PDB entry)

    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [188437] (1 PDB entry)

More info for Family b.42.1.1: Fibroblast growth factors (FGF)

Timeline for Family b.42.1.1: Fibroblast growth factors (FGF):

• Family b.42.1.1: Fibroblast growth factors (FGF) first appeared (with stable ids) in SCOP 1.55
  
• Family b.42.1.1: Fibroblast growth factors (FGF) appears in SCOP 1.75
  
• Family b.42.1.1: Fibroblast growth factors (FGF) appears in SCOPe 2.02
  
• Family b.42.1.1: Fibroblast growth factors (FGF) appears in the current release, SCOPe 2.08