Lineage for Family b.42.1.1: Fibroblast growth factors (FGF)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2053108Fold b.42: beta-Trefoil [50352] (8 superfamilies)
    barrel, closed; n=6, S=12; and a hairpin triplet; meander
    duplication: has internal pseudo threefold symmetry
  4. 2053109Superfamily b.42.1: Cytokine [50353] (3 families) (S)
  5. 2053110Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (10 protein domains)

Protein Domains:

  1. 2053111Acidic FGF (FGF1) [50357] (4 species)
    1. 2053112Species Cow (Bos taurus) [TaxId:9913] [50358] (2 PDB entries)
    2. 2053123Species Eastern newt (Notophthalmus viridescens) [TaxId:8316] [63778] (1 PDB entry)
    3. 2053125Species Human (Homo sapiens) [TaxId:9606] [50359] (94 PDB entries)
      Uniprot P05230 16-152 ! Uniprot P05230
    4. 2053339Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [189149] (1 PDB entry)
  2. 2053342Basic FGF (FGF2) [50355] (1 species)
  3. 2053374Fibrobast growth factor homologous factor 1 (FHF1b, FGF12b) [101776] (1 species)
  4. 2053377Fibroblast growth factor 4 (FGF4) [63779] (1 species)
  5. 2053380Fibroblast growth factor 8, FGF8 [159145] (1 species)
  6. 2053383Fibroblast growth factor 9, FGF9 [63781] (1 species)
  7. 2053390Fibroblast growth factor-10, FGF10 [82107] (1 species)
  8. 2053393Fibroblast growth factor-19 (FGF19) [101778] (1 species)
  9. 2053396Keratinocyte growth factor, FGF7 [50360] (1 species)
  10. 2053401automated matches [190637] (2 species)
    not a true protein
    1. 2053402Species Human (Homo sapiens) [TaxId:9606] [187699] (7 PDB entries)
    2. 2053414Species Norway rat (Rattus norvegicus) [TaxId:10116] [188437] (2 PDB entries)

More info for Family b.42.1.1: Fibroblast growth factors (FGF)

Timeline for Family b.42.1.1: Fibroblast growth factors (FGF):