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Lineage for Protein: Replication protein A 70 KDa subunit (RPA70)

1. Root: SCOP 1.75B

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.40: OB-fold [50198] (16 superfamilies) barrel, closed or partly opened n=5, S=10 or S=8; greek-key

4. Superfamily b.40.4: Nucleic acid-binding proteins [50249] (17 families)

5. Family b.40.4.3: Single strand DNA-binding domain, SSB [50263] (13 protein domains) barrel, closed; n=5, S=10

6. Protein Replication protein A 70 KDa subunit (RPA70) [50267] (1 species) duplication: consists of three domains of this fold; contains zinc-finger insert in the C-terminal domain, residues 479-511

Species:

• Human (Homo sapiens) [TaxId:9606] [50268] (4 PDB entries)

  1. Domain for 1ewi:

     • Domain d1ewia_: 1ewi A: [25302] N-terminal domain only

  2. Domains for 1fgu:

     1. Domain d1fgua1: 1fgu A:181-298 [25296] the N-terminal two domains free

     2. Domain d1fgua2: 1fgu A:299-426 [25297] the N-terminal two domains free

     3. Domain d1fgub1: 1fgu B:181-289 [25298] the N-terminal two domains free

     4. Domain d1fgub2: 1fgu B:298-426 [25299] the N-terminal two domains free

  3. Domains for 1jmc:

     1. Domain d1jmca1: 1jmc A:183-298 [25300] the N-terminal two domains in complex with ssDNA protein/DNA complex

     2. Domain d1jmca2: 1jmc A:299-420 [25301] the N-terminal two domains in complex with ssDNA protein/DNA complex

  4. Domains for 1l1o:

     1. Domain d1l1oc_: 1l1o C: [73480] Other proteins in same PDB: d1l1oa_, d1l1ob_, d1l1od_, d1l1oe_ C-terminal domain only complexed with zn

     2. Domain d1l1of_: 1l1o F: [73483] Other proteins in same PDB: d1l1oa_, d1l1ob_, d1l1od_, d1l1oe_ C-terminal domain only complexed with zn

More info for Protein Replication protein A 70 KDa subunit (RPA70) from b.40.4.3: Single strand DNA-binding domain, SSB

Timeline for Protein Replication protein A 70 KDa subunit (RPA70) from b.40.4.3: Single strand DNA-binding domain, SSB :

Protein Replication protein A 70 KDa subunit (RPA70) from b.40.4.3: Single strand DNA-binding domain, SSB appears in SCOP 1.75A

Copyright © 1994-2013 The SCOP and Astral authors scop@mrc-lmb.cam.ac.uk and astral@compbio.berkeley.edu