SCOP 1.67: Family b.40.4.3: Single strand DNA-binding domain, SSB

Lineage for Family b.40.4.3: Single strand DNA-binding domain, SSB

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.40: OB-fold [50198] (10 superfamilies)
   barrel, closed or partly opened n=5, S=10 or S=8; greek-key

4. Superfamily b.40.4: Nucleic acid-binding proteins [50249] (12 families)

5. Family b.40.4.3: Single strand DNA-binding domain, SSB [50263] (10 proteins)
   barrel, closed; n=5, S=10

Proteins:

1. Archaeal ssDNA-binding protein [89324] (1 species)
   similar to the domains of the Replication protein A

   • Species Archaeon Sulfolobus solfataricus [TaxId:2287] [89325] (1 PDB entry)

2. CDC13 ssDNA-binding domain [74948] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [74949] (2 PDB entries)

3. Core domain of telomere end binding protein beta subunit [50275] (1 species)

   • Species Oxytricha nova [TaxId:200597] [50276] (13 PDB entries)

4. OB-fold domains of BRCA2 [82099] (2 species)
   duplication: tandem repeat of three OB-fold domains

   1. Species Mouse (Mus musculus) [TaxId:10090] [82100] (2 PDB entries)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [82101] (1 PDB entry)

5. Protection of telomeres protein 1, Pot1 [101761] (1 species)

   • Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [101762] (2 PDB entries)

6. Replication protein A 14 KDa (RPA14) subunit [50271] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50272] (2 PDB entries)

7. Replication protein A 32 KDa subunit (RPA32) fragment [50269] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50270] (2 PDB entries)

8. Replication protein A 70 KDa subunit (RPA70) [50267] (1 species)
   duplication: consists of three domains of this fold; contains zinc-finger insert in the C-terminal domain, residues 479-511

   • Species Human (Homo sapiens) [TaxId:9606] [50268] (4 PDB entries)

9. ssDNA-binding protein [50264] (3 species)

   1. Species Escherichia coli [TaxId:562] [50266] (4 PDB entries)

   2. Species Human (Homo sapiens), mitochondria [TaxId:9606] [50265] (1 PDB entry)

   3. Species Mycobacterium tuberculosis [TaxId:1773] [101760] (4 PDB entries)

10. Telomere end binding protein alpha subunit [50273] (1 species)
    duplication: consists of three domains of this fold

    • Species Oxytricha nova [TaxId:200597] [50274] (15 PDB entries)

More info for Family b.40.4.3: Single strand DNA-binding domain, SSB

Timeline for Family b.40.4.3: Single strand DNA-binding domain, SSB:

• Family b.40.4.3: Single strand DNA-binding domain, SSB first appeared (with stable ids) in SCOP 1.55
  
• Family b.40.4.3: Single strand DNA-binding domain, SSB appears in SCOP 1.65
  
• Family b.40.4.3: Single strand DNA-binding domain, SSB appears in SCOP 1.69
  
• Family b.40.4.3: Single strand DNA-binding domain, SSB appears in the current release, SCOPe 2.08