SCOPe 2.05: Family b.40.2.1: Bacterial AB5 toxins, B-subunits

Lineage for Family b.40.2.1: Bacterial AB5 toxins, B-subunits

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.40: OB-fold [50198] (16 superfamilies)
   barrel, closed or partly opened n=5, S=10 or S=8; greek-key

4. Superfamily b.40.2: Bacterial enterotoxins [50203] (3 families)

5. Family b.40.2.1: Bacterial AB5 toxins, B-subunits [50204] (7 proteins)

Proteins:

1. Cholera toxin [50208] (1 species)
   barrel, partly opened; n*=5, S*=10

   • Species Vibrio cholerae [TaxId:666] [50209] (24 PDB entries)
     Uniprot P01556 22-124

2. Heat-labile toxin [50205] (2 species)

   1. Species Escherichia coli, type IB [TaxId:562] [50206] (21 PDB entries)

   2. Species Escherichia coli, type IIB [TaxId:562] [50207] (3 PDB entries)

3. Pertussis toxin S2/S3 subunits, C-terminal domain [50213] (1 species)
   N-terminal domain in S2/S3 has C-lectin-like fold

   • Species Bordetella pertussis [TaxId:520] [50214] (3 PDB entries)

4. Pertussis toxin S4 subunit [50215] (1 species)

   • Species Bordetella pertussis [TaxId:520] [50216] (3 PDB entries)

5. Pertussis toxin S5 subunit [50217] (1 species)

   • Species Bordetella pertussis [TaxId:520] [50218] (3 PDB entries)

6. Verotoxin-1/shiga-toxin, B-pentamer [50210] (4 species)
   phage-borne toxin; bacteriophages H30 and H19B

   1. Species Enterobacteria phage [TaxId:10730] [187110] (1 PDB entry)

   2. Species Escherichia coli [TaxId:562] [50211] (14 PDB entries)

   3. Species Shigella dysenteriae, toxin I [TaxId:622] [50212] (3 PDB entries)
      identical sequence with verotoxin-1 B

   4. Species Shigella dysenteriae, toxin II [TaxId:622] [101755] (1 PDB entry)

7. automated matches [190381] (4 species)
   not a true protein

   1. Species Citrobacter freundii [TaxId:546] [189098] (1 PDB entry)

   2. Species Escherichia coli O157:H7 [TaxId:83334] [189598] (1 PDB entry)

   3. Species Escherichia coli [TaxId:562] [187229] (7 PDB entries)

   4. Species Vibrio cholerae [TaxId:37965] [187230] (1 PDB entry)

More info for Family b.40.2.1: Bacterial AB5 toxins, B-subunits

Timeline for Family b.40.2.1: Bacterial AB5 toxins, B-subunits:

• Family b.40.2.1: Bacterial AB5 toxins, B-subunits first appeared (with stable ids) in SCOP 1.55
  
• Family b.40.2.1: Bacterial AB5 toxins, B-subunits appears in SCOPe 2.04
  
• Family b.40.2.1: Bacterial AB5 toxins, B-subunits appears in SCOPe 2.06
  
• Family b.40.2.1: Bacterial AB5 toxins, B-subunits appears in the current release, SCOPe 2.08