Class b: All beta proteins [48724] (174 folds) |
Fold b.36: PDZ domain-like [50155] (1 superfamily) contains barrel, partly opened; n*=4, S*=8; meander; capped by alpha-helix |
Superfamily b.36.1: PDZ domain-like [50156] (7 families) peptide-binding domain |
Family b.36.1.1: PDZ domain [50157] (47 proteins) Pfam PF00595 |
Afadin [141269] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [141270] (3 PDB entries) Uniprot P55196 985-1079! Uniprot P55196 987-1077 |
Alpha-actinin-2 associated LIM protein [110178] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [110179] (1 PDB entry) Uniprot O70209 4-93 |
Amyloid beta A4 precursor protein-binding family A member 1 (APBA1, X11) [141282] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [141283] (6 PDB entries) Uniprot Q02410 656-740! Uniprot Q02410 657-743! Uniprot Q02410 657-745! Uniprot Q02410 743-822! Uniprot Q02410 745-823! Uniprot Q02410 746-839 structure of the PTB domain is also known (50757) |
Cask/Lin-2 [50160] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [50161] (1 PDB entry) |
Channel associated protein of synapse-110 [141273] (1 species) Discs large homolog 2, PSD-93 |
Species Human (Homo sapiens) [TaxId:9606] [141274] (1 PDB entry) Uniprot Q15700 190-283 |
Discs large 5 protein KIAA0583 [101725] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101726] (1 PDB entry) |
Discs large protein homolog [50158] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [50159] (2 PDB entries) |
DNA Regulating synaptic membrane exocytosis protein 2, RIMS2 [117176] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [117177] (1 PDB entry) Uniprot Q9UQ26 637-754; the structure of the 1st C2 domain (807-934) is also known (101565) |
Enigma homolog ENH [117174] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [117175] (1 PDB entry) Uniprot Q8CI51 5-94 |
Erbin [82085] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [82086] (4 PDB entries) |
Glutamate receptor interacting protein [82083] (2 species) |
Species Mouse (Mus musculus) [TaxId:10090] [110177] (1 PDB entry) Uniprot Q925T6 461-570 |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [82084] (3 PDB entries) |
Glutamate receptor interacting protein 2, GRIP2 (KIAA1719) [110180] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [110181] (2 PDB entries) Uniprot Q9C0E4 238-341 |
Glutamate receptor-interacting protein 1, GRIP1 [101717] (1 species) |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [101718] (2 PDB entries) |
GTPase-binding domain of the cell polarity protein par6 (Par-6B) [89315] (2 species) |
Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [101716] (3 PDB entries) Uniprot O97111 156-253; Cg5884-pa |
Species Mouse (Mus musculus) [TaxId:10090] [89316] (1 PDB entry) |
Harmonin [110182] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [141263] (1 PDB entry) Uniprot Q9Y6N9 201-301 |
Species Mouse (Mus musculus) [TaxId:10090] [110183] (1 PDB entry) Uniprot Q9ES64 741-850 |
hypothetical PDZ domain containing protein Uqcrc2 (4930408O21Rik) [117184] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [117185] (1 PDB entry) Uniprot Q9CR71 8-120 |
Hypothetical protein KIAA0559 [101727] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101728] (1 PDB entry) |
Hypothetical protein KIAA1095 [101723] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101724] (2 PDB entries) Uniprot Q9UPQ7 246-339, 404-512 |
Hypothetical protein KIAA1849 [101729] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101730] (1 PDB entry) |
Inad [63756] (1 species) |
Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [63757] (1 PDB entry) |
KIAA1526 protein [101721] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101722] (3 PDB entries) |
Maguk p55 subfamily member 5 [141275] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [141276] (1 PDB entry) Uniprot Q9JLB2 236-335 Structure of the second L27 domain is known (101293) |
Membrane associated guanylate kinase inverted-2 (MAGI-2, KIAA0705) [101719] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101720] (5 PDB entries) Uniprot Q86UL8 412-522, 600-682, 774-865, 913-1015, 1141-1230 |
Multiple PDZ domain protein [141267] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [141268] (3 PDB entries) Uniprot Q5VZ62 1138-1243! Uniprot Q5VZ62 1955-2042 |
Na+/H+ exchanger regulatory factor, NHERF [63754] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [63755] (4 PDB entries) |
Neurabin-i [141277] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [141278] (1 PDB entry) Uniprot Q9ULJ8 500-593 |
Neuronal nitric oxide synthase, NNOS [50166] (1 species) |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [50167] (3 PDB entries) |
Partitioning-defective 3-like protein, PAR3-L (RIKEN cDNA 2810455b10) [117178] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [117179] (1 PDB entry) Uniprot Q5SV53 478-591 |
PDZ domain containing protein 11, Pdzk11 [117182] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [117183] (1 PDB entry) Uniprot Q9CZG9 37-127 |
PDZ-LIM protein mystique [110186] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [110187] (1 PDB entry) Uniprot Q8R1G6 3-83 |
Phosphatase hPTP1e [50168] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [50169] (5 PDB entries) |
Species Mouse (Mus musculus) [TaxId:10090] [74930] (3 PDB entries) |
Presynaptic protein sap97 [141284] (1 species) PSD-95 homologue |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [141285] (1 PDB entry) Uniprot Q62696 221-313 |
Regulating synaptic membrane exocytosis protein 1, RIMS1 [141279] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [141281] (1 PDB entry) Uniprot Q86UR5 585-694 |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [141280] (1 PDB entry) Uniprot Q9JIR4 597-705 |
Regulator of G-protein signaling 3, RGS3 [117180] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [141264] (1 PDB entry) Uniprot P49796 300-376 |
Species Mouse (Mus musculus) [TaxId:10090] [117181] (1 PDB entry) Uniprot Q9DC04 18-94 |
Rhophilin-2 [110184] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [110185] (1 PDB entry) Uniprot Q8BWR8 506-603 |
Scribble (KIAA0147) [101731] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101732] (3 PDB entries) Uniprot Q14160 680-951, 1096-1193 # structure of 1st PDZ domain is also known, 1XQ5 |
Segment polarity protein dishevelled homolog Dvl-2 [89313] (3 species) |
Species African clawed frog (Xenopus laevis) [TaxId:8355] [89314] (2 PDB entries) |
Species Human (Homo sapiens) [TaxId:9606] [188234] (5 PDB entries) |
Species Mouse (Mus musculus) [TaxId:10090] [101715] (1 PDB entry) |
Shank1, PDZ domain [101733] (1 species) SH3 and multiple ankyrin repeat domains protein 1 |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [101734] (4 PDB entries) |
Synapse-associated protein 102 [101713] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [101714] (2 PDB entries) |
Synaptic protein PSD-95 [50162] (2 species) Synonym: synapse associated protein 90, sap90 duplication: contains three PDZ domains |
Species Human (Homo sapiens) [TaxId:9606] [74932] (1 PDB entry) |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [50163] (8 PDB entries) Uniprot P31016 62-154 |
Syntaxin binding protein 4 [141271] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [141272] (1 PDB entry) Uniprot Q9WV89 12-107 |
Syntenin 1 [89311] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [89312] (11 PDB entries) |
Syntrophin [50164] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [50165] (3 PDB entries) |
Tight junction protein ZO-2, Tjp2 [141265] (1 species) |
Species Mouse (Mus musculus) [TaxId:10090] [141266] (1 PDB entry) Uniprot Q9Z0U1 1-104 |
Tyrosine-protein phosphatase non-receptor type 4, PTPN4 [141286] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [141287] (3 PDB entries) Uniprot P29074 507-612 |
Zasp (Cypher, Oracle 1) [101735] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [101736] (1 PDB entry) |
Species Mouse (Mus musculus) [TaxId:10090] [117173] (1 PDB entry) Uniprot Q9D130 1-83 |
automated matches [190055] (4 species) not a true protein |
Species African clawed frog (Xenopus laevis) [TaxId:8355] [187076] (1 PDB entry) |
Species Human (Homo sapiens) [TaxId:9606] [187785] (13 PDB entries) |
Species Mouse (Mus musculus) [TaxId:10090] [189198] (2 PDB entries) |
Species Norway rat (Rattus norvegicus) [TaxId:10116] [186775] (6 PDB entries) |
Timeline for Family b.36.1.1: PDZ domain: