Lineage for Family b.36.1.1: PDZ domain

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 948106Fold b.36: PDZ domain-like [50155] (1 superfamily)
    contains barrel, partly opened; n*=4, S*=8; meander; capped by alpha-helix
  4. 948107Superfamily b.36.1: PDZ domain-like [50156] (7 families) (S)
    peptide-binding domain
  5. 948108Family b.36.1.1: PDZ domain [50157] (47 proteins)
    Pfam PF00595

Proteins:

  1. 948109Afadin [141269] (1 species)
  2. 948114Alpha-actinin-2 associated LIM protein [110178] (1 species)
  3. 948117Amyloid beta A4 precursor protein-binding family A member 1 (APBA1, X11) [141282] (1 species)
  4. 948126Cask/Lin-2 [50160] (1 species)
  5. 948130Channel associated protein of synapse-110 [141273] (1 species)
    Discs large homolog 2, PSD-93
  6. 948133Discs large 5 protein KIAA0583 [101725] (1 species)
  7. 948136Discs large protein homolog [50158] (1 species)
  8. 948142DNA Regulating synaptic membrane exocytosis protein 2, RIMS2 [117176] (1 species)
  9. 948145Enigma homolog ENH [117174] (1 species)
  10. 948148Erbin [82085] (1 species)
  11. 948155Glutamate receptor interacting protein [82083] (2 species)
    1. 948156Species Mouse (Mus musculus) [TaxId:10090] [110177] (1 PDB entry)
      Uniprot Q925T6 461-570
    2. 948158Species Norway rat (Rattus norvegicus) [TaxId:10116] [82084] (3 PDB entries)
  12. 948163Glutamate receptor interacting protein 2, GRIP2 (KIAA1719) [110180] (1 species)
  13. 948167Glutamate receptor-interacting protein 1, GRIP1 [101717] (1 species)
  14. 948172GTPase-binding domain of the cell polarity protein par6 (Par-6B) [89315] (2 species)
    1. 948173Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [101716] (3 PDB entries)
      Uniprot O97111 156-253; Cg5884-pa
    2. 948177Species Mouse (Mus musculus) [TaxId:10090] [89316] (1 PDB entry)
  15. 948180Harmonin [110182] (2 species)
    1. 948181Species Human (Homo sapiens) [TaxId:9606] [141263] (1 PDB entry)
      Uniprot Q9Y6N9 201-301
    2. 948183Species Mouse (Mus musculus) [TaxId:10090] [110183] (1 PDB entry)
      Uniprot Q9ES64 741-850
  16. 948185hypothetical PDZ domain containing protein Uqcrc2 (4930408O21Rik) [117184] (1 species)
  17. 948188Hypothetical protein KIAA0559 [101727] (1 species)
  18. 948191Hypothetical protein KIAA1095 [101723] (1 species)
  19. 948195Hypothetical protein KIAA1849 [101729] (1 species)
  20. 948198Inad [63756] (1 species)
  21. 948202KIAA1526 protein [101721] (1 species)
  22. 948207Maguk p55 subfamily member 5 [141275] (1 species)
  23. 948210Membrane associated guanylate kinase inverted-2 (MAGI-2, KIAA0705) [101719] (1 species)
  24. 948217Multiple PDZ domain protein [141267] (1 species)
  25. 948225Na+/H+ exchanger regulatory factor, NHERF [63754] (1 species)
  26. 948231Neurabin-i [141277] (1 species)
  27. 948234Neuronal nitric oxide synthase, NNOS [50166] (1 species)
  28. 948239Partitioning-defective 3-like protein, PAR3-L (RIKEN cDNA 2810455b10) [117178] (1 species)
  29. 948242PDZ domain containing protein 11, Pdzk11 [117182] (1 species)
  30. 948245PDZ-LIM protein mystique [110186] (1 species)
  31. 948248Phosphatase hPTP1e [50168] (2 species)
    1. 948249Species Human (Homo sapiens) [TaxId:9606] [50169] (5 PDB entries)
    2. 948260Species Mouse (Mus musculus) [TaxId:10090] [74930] (3 PDB entries)
  32. 948264Presynaptic protein sap97 [141284] (1 species)
    PSD-95 homologue
  33. 948267Regulating synaptic membrane exocytosis protein 1, RIMS1 [141279] (2 species)
    1. 948268Species Human (Homo sapiens) [TaxId:9606] [141281] (1 PDB entry)
      Uniprot Q86UR5 585-694
    2. 948270Species Norway rat (Rattus norvegicus) [TaxId:10116] [141280] (1 PDB entry)
      Uniprot Q9JIR4 597-705
  34. 948272Regulator of G-protein signaling 3, RGS3 [117180] (2 species)
    1. 948273Species Human (Homo sapiens) [TaxId:9606] [141264] (1 PDB entry)
      Uniprot P49796 300-376
    2. 948276Species Mouse (Mus musculus) [TaxId:10090] [117181] (1 PDB entry)
      Uniprot Q9DC04 18-94
  35. 948278Rhophilin-2 [110184] (1 species)
  36. 948281Scribble (KIAA0147) [101731] (1 species)
  37. 948286Segment polarity protein dishevelled homolog Dvl-2 [89313] (3 species)
    1. 948287Species African clawed frog (Xenopus laevis) [TaxId:8355] [89314] (2 PDB entries)
    2. 948295Species Human (Homo sapiens) [TaxId:9606] [188234] (5 PDB entries)
    3. 948305Species Mouse (Mus musculus) [TaxId:10090] [101715] (1 PDB entry)
  38. 948307Shank1, PDZ domain [101733] (1 species)
    SH3 and multiple ankyrin repeat domains protein 1
  39. 948323Synapse-associated protein 102 [101713] (1 species)
  40. 948327Synaptic protein PSD-95 [50162] (2 species)
    Synonym: synapse associated protein 90, sap90
    duplication: contains three PDZ domains
    1. 948328Species Human (Homo sapiens) [TaxId:9606] [74932] (1 PDB entry)
    2. 948330Species Norway rat (Rattus norvegicus) [TaxId:10116] [50163] (8 PDB entries)
      Uniprot P31016 62-154
  41. 948339Syntaxin binding protein 4 [141271] (1 species)
  42. 948342Syntenin 1 [89311] (1 species)
  43. 948377Syntrophin [50164] (1 species)
  44. 948382Tight junction protein ZO-2, Tjp2 [141265] (1 species)
  45. 948385Tyrosine-protein phosphatase non-receptor type 4, PTPN4 [141286] (1 species)
  46. 948394Zasp (Cypher, Oracle 1) [101735] (2 species)
    1. 948395Species Human (Homo sapiens) [TaxId:9606] [101736] (1 PDB entry)
    2. 948397Species Mouse (Mus musculus) [TaxId:10090] [117173] (1 PDB entry)
      Uniprot Q9D130 1-83
  47. 948399automated matches [190055] (4 species)
    not a true protein
    1. 948400Species African clawed frog (Xenopus laevis) [TaxId:8355] [187076] (1 PDB entry)
    2. 948403Species Human (Homo sapiens) [TaxId:9606] [187785] (13 PDB entries)
    3. 948433Species Mouse (Mus musculus) [TaxId:10090] [189198] (2 PDB entries)
    4. 948443Species Norway rat (Rattus norvegicus) [TaxId:10116] [186775] (6 PDB entries)

More info for Family b.36.1.1: PDZ domain

Timeline for Family b.36.1.1: PDZ domain: