Lineage for Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.35: GroES-like [50128] (2 superfamilies)
    contains barrel, partly opened; n*=4, S*=8; meander
  4. Superfamily b.35.1: GroES-like [50129] (3 families) (S)
  5. Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain [50136] (15 proteins)
    C-terminal domain is alpha/beta (classical Rossmann-fold)

Proteins:

  1. 2,4-dienoyl-CoA reductase [89309] (1 species)
  2. Alcohol dehydrogenase [50137] (9 species)
    contains a Zn-finger subdomain, residues 94-117
    1. Species Aeropyrum pernix [TaxId:56636] [101701] (1 PDB entry)
    2. Species Bacillus stearothermophilus [TaxId:1422] [101703] (1 PDB entry)
    3. Species Cod (Gadus callarias) [TaxId:8053] [50141] (1 PDB entry)
    4. Species Frog (Rana perezi) [TaxId:8403] [89305] (2 PDB entries)
    5. Species Horse (Equus caballus) [TaxId:9796] [50138] (52 PDB entries)
      Uniprot P00327
    6. Species Human (Homo sapiens), different isozymes [TaxId:9606] [50139] (24 PDB entries)
      Uniprot P00326 ! Uniprot P00325 ! Uniprot P07327
    7. Species Mouse (Mus musculus), class II [TaxId:10090] [50140] (3 PDB entries)
    8. Species Pseudomonas aeruginosa [TaxId:287] [101702] (1 PDB entry)
    9. Species Sulfolobus solfataricus [TaxId:2287] [82080] (4 PDB entries)
  3. B. subtilis YhfP homologue [117169] (1 species)
  4. Bacterial secondary alcohol dehydrogenase [50142] (2 species)
    1. Species Clostridium beijerinckii [TaxId:1520] [50143] (4 PDB entries)
    2. Species Thermoanaerobacter brockii [TaxId:29323] [50144] (3 PDB entries)
  5. Benzyl alcohol dehydrogenase [89306] (1 species)
  6. Cinnamyl alcohol dehydrogenase, ADH6 [110173] (1 species)
  7. Formaldehyde dehydrogenase [82081] (1 species)
  8. Hypothetical protein TM0436 [101704] (1 species)
  9. Hypothetical protein YahK [101708] (1 species)
  10. Hypothetical protein YhdH [101706] (1 species)
  11. Hypothetical protein YhfP [117171] (1 species)
  12. Ketose reductase (sorbitol dehydrogenase) [50145] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [101710] (3 PDB entries)
    2. Species Silverleaf whitefly (Bemisia argentifolii) [TaxId:77855] [50146] (1 PDB entry)
  13. Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase [110175] (1 species)
  14. Putative zinc-binding alcohol dehydrogenase [101711] (1 species)
  15. Quinone oxidoreductase [50147] (3 species)
    1. Species Escherichia coli [TaxId:562] [50148] (1 PDB entry)
    2. Species Human (Homo sapiens) [TaxId:9606] [117168] (1 PDB entry)
      Uniprot Q08257
    3. Species Thermus thermophilus [TaxId:274] [89308] (2 PDB entries)

More info for Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain

Timeline for Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain: