SCOPe 2.04: Family b.26.1.1: SMAD domain

Lineage for Family b.26.1.1: SMAD domain

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.26: SMAD/FHA domain [49878] (1 superfamily)
   sandwich; 11 strands in 2 sheets; greek-key

4. Superfamily b.26.1: SMAD/FHA domain [49879] (5 families)
   has a few short helices inserted in loops

5. Family b.26.1.1: SMAD domain [49880] (4 proteins)

Proteins:

1. Smad1 [69233] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69234] (1 PDB entry)

2. Smad2 MH2 domain [49883] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49884] (3 PDB entries)

3. Smad3 MH2 domain [82030] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [82031] (3 PDB entries)
     Uniprot P84022 228-425

4. Smad4 tumor suppressor C-terminal domain [49881] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49882] (6 PDB entries)
     Uniprot Q13485 314-546

More info for Family b.26.1.1: SMAD domain

Timeline for Family b.26.1.1: SMAD domain:

• Family b.26.1.1: SMAD domain first appeared (with stable ids) in SCOP 1.55
  
• Family b.26.1.1: SMAD domain appears in SCOPe 2.03
  
• Family b.26.1.1: SMAD domain appears in SCOPe 2.05
  
• Family b.26.1.1: SMAD domain appears in the current release, SCOPe 2.08