Lineage for Superfamily b.26.1: SMAD/FHA domain

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 663035Fold b.26: SMAD/FHA domain [49878] (1 superfamily)
    sandwich; 11 strands in 2 sheets; greek-key
  4. 663036Superfamily b.26.1: SMAD/FHA domain [49879] (4 families) (S)
    has a few short helices inserted in loops

Families:

  1. 663037b.26.1.1: SMAD domain [49880] (4 proteins)
  2. 663070b.26.1.2: FHA domain [49885] (11 proteins)
  3. 663135b.26.1.3: Interferon regulatory factor 3 (IRF3), transactivation domain [101630] (1 protein)
    weak sequence similarity to SMAD domain
  4. 663142b.26.1.4: EssC N-terminal domain-like [141143] (1 protein)
    PfamB 051221 covers two consecutive domains; the first one is of canonical topology, whereas the second domain has a cirular permutation, beginnig at strand 2 and ending at strand 1 of the canonical fold

More info for Superfamily b.26.1: SMAD/FHA domain

Timeline for Superfamily b.26.1: SMAD/FHA domain: