Lineage for Superfamily b.26.1: SMAD/FHA domain

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2042020Fold b.26: SMAD/FHA domain [49878] (1 superfamily)
    sandwich; 11 strands in 2 sheets; greek-key
  4. 2042021Superfamily b.26.1: SMAD/FHA domain [49879] (5 families) (S)
    has a few short helices inserted in loops

Families:

  1. 2042022b.26.1.1: SMAD domain [49880] (5 protein domains)
  2. 2042055b.26.1.2: FHA domain [49885] (12 protein domains)
  3. 2042125b.26.1.3: Interferon regulatory factor 3 (IRF3), transactivation domain [101630] (1 protein)
    weak sequence similarity to SMAD domain
  4. 2042136b.26.1.4: EssC N-terminal domain-like [141143] (1 protein)
    PfamB PB051221 covers two consecutive domains; the first one is of canonical topology, whereas the second domain has a cirular permutation, beginnig at strand 2 and ending at strand 1 of the canonical fold
  5. 2042141b.26.1.0: automated matches [191616] (1 protein)
    not a true family

More info for Superfamily b.26.1: SMAD/FHA domain

Timeline for Superfamily b.26.1: SMAD/FHA domain: