SCOP 1.75: Protein: Tumor necrosis factor (TNF)

Lineage for Protein: Tumor necrosis factor (TNF)

Root: SCOP 1.75
Class b: All beta proteins [48724] (174 folds)
Fold b.22: TNF-like [49841] (1 superfamily)
sandwich, 10 strands in 2 sheets; jelly-roll
Superfamily b.22.1: TNF-like [49842] (1 family)
Family b.22.1.1: TNF-like [49843] (14 proteins)
Protein Tumor necrosis factor (TNF) [49848] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [49849] (7 PDB entries)
1. Domains for 1a8m:
  1. Domain d1a8ma_: 1a8m A: [23868]
  2. Domain d1a8mb_: 1a8m B: [23869]
  3. Domain d1a8mc_: 1a8m C: [23870]
    mutant
2. Domains for 1tnf:
  1. Domain d1tnfa_: 1tnf A: [23871]
  2. Domain d1tnfb_: 1tnf B: [23872]
  3. Domain d1tnfc_: 1tnf C: [23873]
3. Domain for 1tnr:
  - Domain d1tnra_: 1tnr A: [23867]
    Other proteins in same PDB: d1tnrr1, d1tnrr2, d1tnrr3
4. Domains for 2az5:
  1. Domain d2az5a1: 2az5 A:10-157 [127599]
    automatically matched to d1tnfa_
    complexed with 307
  2. Domain d2az5b1: 2az5 B:10-157 [127600]
    automatically matched to d1tnfa_
    complexed with 307
  3. Domain d2az5c1: 2az5 C:10-157 [127601]
    automatically matched to d1tnfa_
    complexed with 307
  4. Domain d2az5d1: 2az5 D:10-157 [127602]
    automatically matched to d1tnfa_
    complexed with 307
5. Domains for 2tun:
  1. Domain d2tuna_: 2tun A: [23874]
  2. Domain d2tunb_: 2tun B: [23875]
  3. Domain d2tunc_: 2tun C: [23876]
  4. Domain d2tund_: 2tun D: [23877]
  5. Domain d2tune_: 2tun E: [23878]
  6. Domain d2tunf_: 2tun F: [23879]
    mutant
6. Domain for 4tsv:
  - Domain d4tsva_: 4tsv A: [23860]
    mutant
7. Domains for 5tsw:
  1. Domain d5tswa_: 5tsw A: [23861]
  2. Domain d5tswb_: 5tsw B: [23862]
  3. Domain d5tswc_: 5tsw C: [23863]
  4. Domain d5tswd_: 5tsw D: [23864]
  5. Domain d5tswe_: 5tsw E: [23865]
  6. Domain d5tswf_: 5tsw F: [23866]
    mutant
Mouse (Mus musculus) [TaxId:10090] [49850] (1 PDB entry)
- Domains for 2tnf:
  1. Domain d2tnfa_: 2tnf A: [23880]
  2. Domain d2tnfb_: 2tnf B: [23881]
  3. Domain d2tnfc_: 2tnf C: [23882]
    complexed with ipa, trs

More info for Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like

Timeline for Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like:

Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like first appeared (with stable ids) in SCOP 1.55
Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like appears in SCOP 1.73
Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like appears in SCOPe 2.01
Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like appears in the current release, SCOPe 2.08