Lineage for Family b.22.1.1: TNF-like

  1. Root: SCOP 1.69
  2. 450777Class b: All beta proteins [48724] (144 folds)
  3. 459440Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 459441Superfamily b.22.1: TNF-like [49842] (1 family) (S)
  5. 459442Family b.22.1.1: TNF-like [49843] (11 proteins)

Proteins:

  1. 45944330 kDa adipocyte complement-related protein [49846] (1 species)
  2. 459454Apoptosis-2 ligand, apo2l/TRAIL [49851] (1 species)
  3. 459468Collagen NC1 trimerisation domain [69230] (2 species)
    1. 459469Species Human (Homo sapiens), isoform X [TaxId:9606] [69231] (1 PDB entry)
    2. 459471Species Mouse (Mus musculus), isoform VIII [TaxId:10090] [101612] (1 PDB entry)
  4. 459475Complement c1q globular head, A chain [101613] (1 species)
    hetrotrimer of A, B and C chains
  5. 459478Complement c1q globular head, B chain [101615] (1 species)
    hetrotrimer of A, B and C chains
  6. 459481Complement c1q globular head, C chain [101617] (1 species)
    hetrotrimer of A, B and C chains
  7. 459484Ectodysplasin A, Eda-a1 [101610] (1 species)
  8. 459504Extracellular domain of CD40 ligand [49844] (1 species)
  9. 459510Soluble part of TALL-1, sTALL-1 (BAFF) [69228] (1 species)
    • 459511Species Human (Homo sapiens) [TaxId:9606] [69229] (6 PDB entries)
      also includes the PDB entry (1otz) that together with the entry (1p0t) provides the multimeric structure of the complex of this protein with its receptor, BAFF-R. In these entries protein chains are designated by both upper case and lower case letters creating problems with its processing and presentation in SCOP
  10. 459560TRANCE/RANKL cytokine [63721] (1 species)
  11. 459568Tumor necrosis factor (TNF) [49848] (2 species)
    1. 459569Species Human (Homo sapiens) [TaxId:9606] [49849] (6 PDB entries)
    2. 459590Species Mouse (Mus musculus) [TaxId:10090] [49850] (1 PDB entry)

More info for Family b.22.1.1: TNF-like

Timeline for Family b.22.1.1: TNF-like: